BPC3 Genotyping Resources
Genotyping for BPC3's current genome-wide association studies (GWAS) is occurring are three Genomics Centers:
- Centre d'Etude du Polymorphisme Humain
(CEPH)
For more information, contact Dr. Gilles Thomas - The Broad Institute of MIT and
Harvard
For more information, contact Dr. David Altshuler - NCI Core Genotyping Facility
For more information, contact Dr. Stephen Chanock
All of the sequencing and genotyping data generated in BPC3 are publicly available
at the USC/Norris Comprehensive
Cancer Center web site. These include:
- sequencing data used to select tag SNPs in 75 candidate genes in the sex steroid hormone and IGF-1 growth factor pathways;
- selection of haplotype tagging SNPs for these genes;
- Haploview plots showing the linkage disequilibrium across each locus; and
- output from Tagger with the tagging SNPs chosen.
Information is also provided on the primers and probes for each TaqMan assay, and sample Taqman scatterplots from each genotyping center.
