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from the office of Deborah Winn, Pd.D., Acting Associate Director EGRP

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 News Flash, July 11, 2008

NIH Director Announces Enhancements to Peer Review

The National Institutes of Health (NIH) has announced critical changes to enhance and improve the NIH peer review system. An important component of the new plan is an increased commitment to investigator-initiated high-risk, high-impact research to prevent a slowdown of transformative research, despite difficult budgetary times.

The initiatives reflect NIH's response to thousands of comments, opinions, and criticisms received throughout the year. Taken together, these proposals bring to fruition the original charge to fund the best science, by the best scientists, with the least administrative burden.

Collaborative teams of participants worked to tackle challenges of the system and discover solutions. A comprehensive framework was created and implementation will be carried out over the next 18 months. The Implementation Plan Report consists of four main priorities and highlights include:

  • Priority 1 – Engage the Best Reviewers: Increase flexibility of service, formally acknowledge reviewer efforts, further compensate time and effort, and enhance and standardize training
  • Priority 2 – Improve Quality and Transparency of Reviews: Shorten and redesign applications to highlight impact and to allow alignment of the application, review and summary statement with five explicit review criteria, and modify the rating system
  • Priority 3 – Ensure Balanced and Fair Reviews Across Scientific Fields and Career Stages
    • Support a minimum number of early stage investigators and investigators new to NIH, and emphasize retrospective accomplishments of experienced investigators;
    • Encourage and expand the Transformative Research Pathway;
    • Create a new investigator-initiated Transformative R01 Award program funded within the NIH Roadmap with an intended commitment of a minimum of $250 million over five years;
    • Continue the commitment of—and possibly expand the use of—the Pioneer, EUREKA, and New Innovator Awards. NIH will invest at least $750 million in these three programs over the next 5 years; and
    • Reduce the burden of multiple rounds of resubmission for the same application, especially for highly meritorious applications.
  • Priority 4 – Develop a Permanent Process for Continuous Review of Peer Review

For more information about enhancing peer review at NIH and to learn about the implementation plan, please visit http://enhancing-peer-review.nih.gov.


 News Flash, June 10, 2008

Reminder for NIH Study Section Members Planning to Submit Grant Applications with Budgets of $500,000 or More in Direct Costs in Any Given Year to Consult with Their Program Directors

In January 2008, the National Institutes of Health (NIH) announced a modified application submission, referral and review process for appointed NIH Study Section Members (see NIH Notice NOT-OD-08-026) planning to submit R01, R21, and R34 applications. Despite the alternate submission and review procedures for appointed study section members and ad hoc members (see NIH Notice NOT-08-027), the Awaiting Receipt of Application (ARA) process still applies when budget requests are likely to be submitted with direct costs >$500,000 in any given year. Applicants who are eligible for the alternate grant application submission procedures still must seek agreement from Institute/Center staff to accept assignment prior to the anticipated submission of any application (see NIH Notice, NOT-OD-02-004). Therefore, the Epidemiology and Genetics Research Program (EGRP) recommends that current and prospective grantees who serve on NIH Study Sections continue to contact EGRP Program Directors well in advance to discuss their submission plans and timelines for grant applications. Contact information for EGRP Program Directors.

Review of Key Web pages:


 News Flash, June 6, 2008

Funding Opportunity Announcements: Biomarkers of Infection-Associated Cancers

On behalf of the National Cancer Institute (NCI) and the National Institute of Dental and Craniofacial Research (NIDCR), NCI’s Epidemiology and Genetics Research Program (EGRP) announces two funding opportunity announcements (FOAs), that encourage the submission of Research Project Grant (R01) applications and Exploratory/Developmental Grant (R21) applications from institutions and organizations that propose to identify biomarkers for cancers where the etiology of the disease is attributed to infectious agents.

The objectives of these FOAs are to foster research to increase our knowledge of infectious agent-associated malignancies and identify those who are at increased risk of developing cancer among infected individuals and to detect early stage cancers in this population. The long-term goal of these FOAs is to encourage research that will increase our knowledge of infectious agent-associated malignancies and utilization of molecular profiles in early detection, risk assessment, and prevention of cancer. Listed below, but not limited to, are several programmatic areas in need of support for developing molecular signatures for infectious agent-associated cancers.

  • Molecular profiles of normal, precancerous, and cancerous lesions following infection and of body fluids from infected individuals.
  • Evaluation of these molecular profiles for use in gaining a better understanding of the role of infectious agents in cancer development and use in early detection, risk assessment, and prevention of cancer.

Awards issued under these FOAs are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications; therefore, the anticipated number of awards is not known. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received.

R01 applicants requesting $500,000 or more in direct costs for any year (excluding consortium F&A costs) must carry out the following steps:

  1. Contact the appropriate NIH institute or center (IC) program staff member(s) at least 6 weeks before submitting the application, i.e., as plans are being developed for the study;
  2. Obtain agreement from the IC staff member that the IC will accept the application for consideration for award; and
  3. Include a cover letter with the application that identifies the staff member and IC that agreed to accept assignment of the application.

The total project period for R21 applications submitted in response to this funding opportunity may not exceed two years. Direct costs are limited to $275,000 over an R21 two-year period, with no more than $200,000 in direct costs allowed in any single year. The R21 is not renewable.  Both FOAs expire May 8, 2011. Standard application submission and receipt dates apply.  

The NCI cosponsors for these FOAs include the Division of Cancer Prevention and the Division of Cancer Biology.  Please refer to the FOAs for the scientific contacts.

Access the NIH GUIDE FOR GRANTS AND CONTRACTS


 News Flash, June 4, 2008

This News Flash from NCI’s Epidemiology and Genetics Research Program (EGRP) brings you news about:

  • Comments on NIH’S Mandatory Public Access Policy for Publications Due By May 31; Apply for AIDS-Associated Supplements by June 15
  • Requests for Supplements to Existing NCI Projects for Collaborations in AIDS-Associated Malignancies Due By June 15

 News Flash, April 29, 2008

Request for Information: Ideas for NIH Common Fund / Roadmap Initiatives

The National Institutes of Health (NIH)'s Office of Portfolio Analysis and Strategic Initiatives is seeking input from the scientific community, health professionals, patient advocates, and the general public about innovative and cross - cutting initiatives to be funded through the NIH Common Fund. The Common Fund / Roadmap supports programs that address fundamental knowledge gaps, develop transformative tools and technologies, and/or foster innovative approaches to complex problems. These programs are supported for a limited duration of 5-10 years. Collecting ideas is an initial step in the process of identifying a new cohort of Common Fund / Roadmap programs for Fiscal Year 2011. The NIH expects to spend $30 - 50 million per year from within the currently projected budget for new 5-year initiatives.

Because NIH Institutes and Centers (ICs) regularly collaborate in areas of shared interest, the IC Directors and the NIH Leadership developed specific criteria for Common Fund / Roadmap programs. Primary among these criteria is that the programs are expected to have exceptionally high impact and to transform the way research is conducted. All Common Fund / Roadmap programs are relevant to multiple diseases. All ideas should meet the following criteria for new trans-NIH strategic initiatives:

  • Is the proposed initiative truly transforming - could it dramatically affect how biomedical and/or behavioral research is conducted over the next decade?
  • Will the outcomes from the proposed initiatives synergistically promote and advance the individual missions of the Institutes and Centers to benefit health?
  • Does the proposed initiative require participation from NIH as a whole and/or does it address an area (s) of science that does not clearly fall within the mission of any one IC or OD program office?
  • Is the proposed initiative something that no other entity is likely or able to do, and is there a public health benefit to having the results of the research in the public domain?

Responses will be accepted through Friday, June 2, 2008. Please limit your response to 1 page. To submit a response, please e-mail roadmap_ideas@nih.gov

Access the NIH Guide for Grants and Contracts for details: NOT-RM-08-014.


 News Flash, April 22, 2008

Two Funding Opportunities Announced For Mitochondria Research In Cancer Epidemiology, Detection, Diagnosis, And Prognosis

The National Cancer Institute (NCI) is sponsoring two Program Announcements to stimulate the development and validation of novel mitochondrial (mt) DNA biomarkers for understanding etiology, early detection, diagnosis, prognosis, and risk assessment of cancer, and response to preventive and ameliorative treatment. The PAs invite applications using the Research Project Grant (R01) and the Exploratory/Developmental Grants (R21) funding mechanisms. The Epidemiology and Genetics Research Program (EGRP) is the initiator and a cosponsor of these PAs.

Some of the specific research questions that may be addressed in response to these PAs include, but are not limited to, the following:

  • Are mitochondrial markers useful for identification of high risk groups before clinical onset of disease?
  • Are mitochondrial characteristics or haplotypes associated with risk of developing cancer? If so, can this help explain racial and ethnic differences in cancer risk?
  • Are there modifiable factors or host factors that influence the relationship between mtDNA characteristics and cancer risk?
  • Are mitochondria correlated with intermediate disease states in the neoplastic pathway, such as precursor lesions?
  • Are genetic and mtDNA alterations (somatic mutations, deletions) correlated during cancer development?
  • Can the character of mtDNA anticipate the potential aggressiveness of malignancy?
  • How can mitochondrial markers be utilized to predict disease progression and identify novel therapeutic targets?
  • Can we advance the technology for high-throughput analysis and imaging of mitochondrial clustering?
  • Are there unique mtDNA mutations associated with specific types of cancers?
  • How early can mtDNA mutations be detected - can they be detected in pre-malignant lesions such as PIN?
  • Can a diagnostic assay based on mutations in mtDNA alone or in combination with other markers be developed for noninvasive detection and/or monitoring of cancer?
  • Can nutrition or chemopreventive agents ameliorate genetic effects of mitochondrial activity induced mutational events?

Because the nature and scope of the proposed research will vary, it is anticipated that the size and duration of each award will also vary. The total project period for R21 applications submitted in response to this funding opportunity announcement may not exceed two years and direct costs are limited to $275,000 over the two-year period, with no more than $200,000 in direct costs allowed in any single year. Standard application submission and receipt dates apply. Both PAs expire on May 8, 2011.

The contact for general questions about epidemiology is EGRP's Mukesh Verma, Ph.D., Chief, Methods and Technologies Branch, and Acting Chief, Host Susceptibility Factors Branch; e-mail: vermam@mail.nih.gov.

Also cosponsoring these PAs are NCI's Division of Cancer Prevention (DCP), Division of Cancer Treatment and Diagnosis (DCTD), and the Office of the Director (OD). Please refer to the PAs for the scientific contacts.

Access the NIH Guide for Grants and Contracts for details: PA-08-143 (R01), and PA-08-144 (R21)


 News Flash, April 18, 2008

FAQs Available About Administrative Supplements for Gene Identification Efforts

Last month, the Epidemiology and Genetics Research Program (EGRP) announced the availability of administrative supplements for NIH-funded genetic association studies aimed at identifying genetic factors involved in complex trait etiology. A set of Frequently Asked Questions and Answers for applicants is now available. Requests for supplements are due by May 1, 2008.

All current NIH awardees of R01, P01, and P50 grants, and U01, U19, and U54 cooperative agreements are eligible provided specific conditions are met. This opportunity is part of the NIH-wide Genes, Environment, and Health Initiative (GEI), in which all NIH Institutes and Centers participate.

The supplements are to provide support for replication studies (with or without fine-mapping) of genetic regions putatively associated with the studied complex trait(s) (primarily those identified by genome-wide association studies (GWAS)) in order to maximize the productivity of NIH-funded GWAS.

Priority funding will be given to studies with one of more of the following characteristics: synergy with NIH’s Gene Environment Association Studies, breadth of available phenotypic and exposure measures for study participants, and plans for sharing data with the research community. Studies should focus on replication in the original discovery population if little replication information is available to date. If the original “hit” has been sufficiently replicated, studies should focus on populations not included in the initial GWAS or subsequent replication studies, such as groups with different environmental exposures.

Budget requests must not exceed $400,000 in total costs for funding not to exceed 12 months. Please note that the NIH Center for Scientific Review (CSR) is not involved in receipt and processing of these requests. NCI's EGRP will receive these administrative supplement requests. See instructions.

Contact: Elizabeth Gillanders, Ph.D., Program Director, Host Susceptibility Factors Branch, EGRP; e-mail: lgilland@mail.nih.gov


 News Flash, April 10, 2008

NIH Seeks Info on Pharmacogenomics by April 20th

We thought you might be interested in an opportunity to respond to a Request for Information (RFI) on challenges and barriers to pharmacogenomics research. The request is from the Trans-NIH Pharmacogenomics Working Group. The RFI is in the form of an on-line series of questions intended to reveal gaps and highlight opportunities in pharmacogenomics, and to aid in identifying specific, achievable goals that will advance and transform the field overall. NIH wants to consider research needs from discovery-based efforts to validation and applied research, in order to accelerate the translation of pharmacogenomics discoveries into the clinical realm.

NIH is interested in responses that suggest transformative ideas and approaches. The best ideas will have great potential to dramatically affect how biomedical research is conducted over the next decade, yet will be concrete and achievable tasks. Moreover, NIH wants to leverage existing research mechanisms and resources. Ideas for enabling research efforts of interest would be those challenges to pharmacogenomics that: (1) are activities that no other entity is likely to be able to successfully conduct, (2) will generate knowledge that can be made publicly accessible, and (3) are of clear benefit to public health.

Responses must be submitted electronically at http://www.nigms.nih.gov/Initiatives/NIH-RFI and will be accepted through April 30, 2008.

Contact: Rochelle M. Long, Ph.D., Chief, Pharmacology & Physiological Sciences Branch; Pharmacology, Physiology, & Biological Chemistry Division, National Institute of General Medical Sciences (NIGMS), e-mail: Rochelle.long@nih.gov.

Access the NIH Guide for Grants and Contracts for details: NOT-GM-08-125.


 News Flash, April 3, 2008

Policy of the National Cancer Institute for Allowable Requested Budget Levels of Competing Continuation (Type 2) R01, U01 and P01 Applications

The Epidemiology and Genetics Research Program (EGRP) reminds current and prospective grantees that NCI restricts all competing continuation (Type 2) R01, U01 and P01 applications to a 20% increase over the last funding period. In cases where the last non-competing year may be substantially lower than previous years, applicants may cite the average yearly direct cost for the previous funding period as the base for the policy cap on the Type 2 applications. Type 2 applications that are within the pay line or selected for funding by exception that do not conform to the cap will be subject to a reduction in the total budget to align it with the NCI Type 2 policy, in addition to the current NCI programmatic reductions and applicable Study Section/Integrative Review Group recommended reductions.

Answers to frequently asked questions are available for R01s and U01s. For questions about P01s, contact an EGRP Program Director.

Access the NIH Guide for Grants and Contracts for details:


 News Flash, March 14, 2008

Funding Opportunity Announcement: Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network

On behalf of the NIH Office of Rare Diseases (ORD), NCI's Epidemiology and Genetics Research Program (EGRP) announces a Request for Applications (RFA) for new and renewal cooperative agreement applications (U54) for Rare Diseases Clinical Research Consortia (RDCRC). Proposals are sought for RDCRCs that individually focus on a subset of related rare diseases.

Each RDCRC will consist of a consortium of clinical investigators, institutions, and relevant organizations, including patient support organizations, focused on a subgroup of rare diseases. Support is provided for 1) collaborative clinical research in rare diseases, including longitudinal studies of individuals with rare diseases, clinical studies and/or phase I, II, and II/III trials; 2) training of clinical investigators in rare diseases research; 3) pilot and demonstration projects 4) a test bed for distributed clinical data management that incorporates novel approaches and technologies for data management, data mining, and data sharing across rare diseases, data types, and platforms; and 5) access to information related to rare diseases for basic and clinical researchers, academic and practicing physicians, patients, and the lay public.

Required components of a RDCRC application include:

  • A minimum of two clinical research projects (at least one of them must be a longitudinal study);
  • A training (career development) component;
  • At least one pilot/demonstration project;
  • A Web site for educational and research resources in rare diseases;
  • Collaboration with patient support organization(s); and
  • An administrative unit

The NIH ORD and participating NIH Institutes and Centers intend to commit approximately $8.75 million in Fiscal Year 2009 to fund up to seven new and/or renewal grant applications for RDCRCs. If additional funds become available, approximately ten consortia may be funded. An applicant must request a project period for five years. In general, budget requests should be limited to $1.25 million in total cost.

Letters of Intent are due July 20, and applications are due by August 20, 2008.

Contact: Elizabeth Read-Connole, Ph.D., NCI Representative to the Office of Rare Diseases Committee; email bconnole@mail.nih.gov.

Access the NIH Guide for Grants and Contracts for details: RFA-OD-08-001.


 News Flash, March 6, 2008

Administrative Supplements for Gene Identification Efforts: Replication and Fine-Mapping Studies: The Genes, Environment, and Health Initiative (GEI)

On behalf of the NIH-wide Genes, Environment, and Health Initiative (GEI), NCI’s Epidemiology and Genetics Research Program (EGRP) announces the availability of administrative supplements for NIH-funded genetic association studies aimed at identifying genetic factors involved in complex trait etiology. The purpose of this funding opportunity is to provide support for replication studies (with or without fine-mapping) of genetic regions putatively associated with the studied complex trait(s) (primarily those identified by genome-wide association studies (GWAS)) in order to maximize the productivity of NIH-funded GWAS. This opportunity is open to all current NIH awardees of R01, P01, and P50 grants, and U01, U19, and U54 cooperative agreements, provided specific conditions are met. Learn more about the GEI initiative.

Priority funding will be given to studies with one of more of the following characteristics: synergy with NIH’s Gene Environment Association Studies, breadth of available phenotypic and exposure measures for study participants and plans for sharing data with the research community. Studies should focus on replication in the original discovery population if little replication information is available to date. If the original “hit” has been sufficiently replicated, studies should focus on populations not included in the initial GWAS or subsequent replication studies, such as groups with different environmental exposures.

Requests are due by May 1, 2008. Budget requests must not exceed $400,000 in total costs for funding not to exceed 12 months. Please note that the NIH Center for Scientific Review (CSR) is not involved in receipt and processing of these requests. NCI's EGRP will receive these administrative supplement requests. Detailed application instructions.

Contact: Elizabeth Gillanders, Ph.D., Program Director, Host Susceptibility Factors Branch; e-mail: lgilland@mail.nih.gov.

Access the NIH Guide for Grants and Contracts for details: NOT-CA-08-011: Administrative Supplements for Gene Identification Efforts: Replication and Fine-Mapping Studies for the Genes, Environment, and Health Initiative (GEI)


 News Flash, February 25, 2008

Request for Applications Announced for Comparative Systems Genetics of Cancer

The National Cancer Institute (NCI), in collaboration with the National Institute of Environmental Health Sciences (NIEHS), has announced a Request for Applications (RFA) for grant applications for research projects (R01s) focused on the development and application of comparative (cross-species) systems genetics approaches to address key cancer-relevant problems. Proposals are sought for research projects that will use these approaches to enhance the understanding of the mechanisms that underlie (1) human cancer susceptibility and (2) heterogeneity of human tumors.

To meet these two goals, proposed projects are expected to involve appropriate interdisciplinary collaborations providing expertise in such areas as human genetics, statistical genetics, model organism genetics, systems biology, mathematical or computational modeling of biological processes, and computer sciences. All projects are required to propose use of two species, one of which must be human, and projects must adhere to the cancer Biomedical Informatics Grid (caBIG™) standards.

Examples of research topics for investigation may include, but are not limited to, the following areas:

  • Characterize the genetic networks that produce the variable manifestations of a specific human cancer;
  • Integrate available genome-wide association studies (GWAS) and model organism genetic data into a testable, system-level model of a specific human cancer;
  • Determine mechanisms of genetic perturbations by environmental factors in a specific human cancer
  • Evaluate data models that incorporate genetic and environmental factors to refine phenotypes that enable subcategorization of a specific human cancer;
  • Develop and test data models that account for the interaction of genotype and environment in determining phenotypic responses to the environment that may be related to human cancer;
  • Determine the influence of genetic variation on systems-level responses to environmental factors relevant to cancer in humans;
  • Understand mechanisms of perturbations of pathways implicated in environmentally induced diseases;
  • Develop and test models to predict toxicological responses in highly connected genes and disease pathways that are evolutionarily conserved; and
  • Understand susceptibility to toxic compounds in model organisms and humans.

NCI intends to commit about $3 million per year for up to 5 years to fund four to six individual multidisciplinary research programs. The NCI sponsors are EGRP, which is part of the Division of Cancer Control and Population Sciences (DCCPS), and the Division of Cancer Biology (DCB).

Programmatic inquiries may be directed to: Mukesh Verma, Ph.D., Chief, Methods and Technologies Branch (MTB), EGRP, NCI, e-mail: vermam@mail.nih.gov; Cheryl Marks, Ph.D., Associate Director, DCB, NCI, e-mail: marksc@mail.nih.gov; and Kimberly McAllister, Ph.D., Program Administrator, NIEHS, e-mail: mcallis2@niehs.nih.gov.

Read the complete RFA, RFA-CA-08-017, in the NIH Guide for Grants and Contracts.


 News Flash, February 11, 2008

NCI Epidemiology and Genetics Research Program Seeks Program Directors

The Epidemiology and Genetics Research Program (EGRP), Division of Cancer Control and Population Sciences (DCCPS), National Cancer Institute (NCI), has two openings for cancer epidemiologists. Program Directors develop, coordinate, and manage a national and international extramural research portfolio of grants in cancer epidemiology and identify research opportunities that lead to new scientific initiatives. The positions offer wonderful opportunities for those who are interested in helping to shape the direction of cutting-edge cancer epidemiology research. Successful candidates will have significant leadership and collaborative opportunities with NCI scientists on important scientific initiatives related to cancer epidemiology, including but not limited to cancer control, cancer research consortia, cancer genetics, health disparities, etc.

NCI is part of the National Institutes of Health (NIH), U.S. Department of Health and Human Services (DHHS). EGRP is the largest funder of etiologic cancer epidemiology grants nationally and worldwide. It supports epidemiologic research in four areas: methods and technologies for epidemiologic studies; modifiable risk factors (e.g., energy balance and environmental and infectious agent exposures); host susceptibility risk factors (e.g., social, genetic, and race/ethnicity factors); and clinical and translational research (e.g., risk factors for second primary cancers and the effects of prophylactic approaches). EGRP's offices are located in Rockville, MD, a suburb of Washington, DC. Further information about EGRP.

Qualifications: U.S. citizenship is a requirement. A doctoral degree and formal training in epidemiology are required. Candidates must have: knowledge of epidemiologic research methodologies necessary to develop epidemiologic research studies; ability to administer, conduct, and evaluate multidisciplinary epidemiologic research; skill in oral communication as it pertains to a research area; and skill in written communication as it pertains to a research program area.

Salary range: The positions are available at the GS 13/14 level, for which the 2008 pay range is $82,961-$127,442 per year. Relocation expenses may be paid.

The position is advertised on the USAJOBS Web site as Health Scientist Administrator (Epidemiologist). To be considered for this position, candidates must formally apply through the Web site. The deadline for applications is March 5, 2008. Access the complete announcement and application materials by inserting in the keyword search box the following announcement number: NCI-08-241044-DE. After beginning the online application process through the above announcement number, Federal government status candidates will be guided to apply under announcement number NCI-08-241044-MP.

Inquiries about this position may be directed to the Personnel Officer named in the announcements: Ms. Anne Solomon, tel.: 301-496-8737; fax: 301- 496 6168; e-mail: ncihrmcbapps@mail.nih.gov .


 News Flash, February 7, 2008

Supplements Offered for Dissemination of Cancer-Related Surveillance Research

Our Division of Cancer Control and Population Sciences (DCCPS) is sponsoring administrative supplements for dissemination of cancer-related surveillance research. Current National Cancer Institute (NCI) awardees of R01, P01, P50, U01, and U19 grants pertaining to cancer control are eligible to apply provided the conditions listed below are met. The application deadline is April 1, 2008.

The conditions are:

  1. The topic area of the original cancer control award must be related to the focus of the surveillance research/surveillance data analysis that is being proposed in the supplement request (for example, if the parent grant focuses on physical activity, the supplement should focus on the dissemination of surveillance data on physical activity);
  2. The proposed surveillance dissemination effort must clearly be beyond the scope of the “parent” award;
  3. The “parent” award must remain active during the entire funding period of this supplement; and
  4. The Principal Investigator (PI) for the supplement must be the PI of the “parent” award.

Diverse aspects of cancer control might be appropriate for dissemination efforts under these supplements (for example, cancer risk factors, screening, cancer rates, treatment, and outcomes). Specific areas include, but are not limited to:

  • tobacco use;
  • diet and physical activity patterns;
  • sun exposure and ultraviolet radiation exposure;
  • use of chemopreventive agents;
  • use of genetic testing for cancer susceptibility;
  • use of screening for breast, cervix, and colorectal cancers;
  • cancer rates, morbidity, and mortality;
  • cancer treatment and patterns of care; and
  • cancer outcomes.

The goals of these supplements are to:

  1. Fund innovative dissemination of surveillance research results to increase application of these results in policy, practice, and communities across the cancer continuum;
  2. Encourage surveillance researchers to develop and test ways to expand use of their data;
  3. Encourage researchers and program planners in other areas, such as communication and intervention research, to consider ways to use surveillance data in their research or programs; and
  4. Encourage transdisciplinary collaborations between researchers in surveillance and other areas, such as communications and interventions.

NCI intends to commit about $200,000 in FY 2008 to fund about two (2) administrative supplements in response to this initiative. Budget requests must not exceed $100,000 in total costs for a funding period not to exceed 12 months.

Access the NIH Guide for Grants and Contracts Notice (NOT-CA-08-008), for Frequently Asked Questions, and detailed instructions on applying.

Requests for these administrative supplements must be submitted to DCCPS by the April 1 due date. Note that the National Institutes of Health’s (NIH) Center for Scientific Review (CSR) is not involved in receipt and processing of these requests.


 News Flash, February 5, 2008

NIH Announces Manufacturing Assistance Program (MAP) for Its Phase II SBIR Awardees

The National Institutes of Health (NIH) announced the availability of a Manufacturing Assistance Program (MAP) for its Small Business Innovation Research (SBIR) Phase II awardees from 2003 to the present. We want to be sure that you are aware of this opportunity. This new program is designed to help SBIR awardees identify, address, and develop a strategy to overcome the manufacturing issues related to the commercialization of their SBIR-developed products. (NOTE: This program is not available to Small Business Technology Transfer [STTR] awardees.) Applications are due February 14, 2008; however, if you’re interested, act quickly as the first 30 applications received will be considered for the 25 slots that are available.

Review the NIH Guide Notice NOT-OD-08-025 (released Dec. 28, 2007) for the program’s full description and the application form.


 Bulletin, January 29, 2008

  • EGRP Seeks Two Branch Chiefs and Additional Program Directors
  • EGRP Staff News
    • Virginia (Ginny) Hartmuller, Ph.D., R.D., Retires
    • Elizabeth (Liz) Gillanders, Ph.D., Joins as Program Director
    • Michael Donovan, Ph.D., Does Rotation as Presidential Management Fellow
    • Damali Martin, Ph.D., M.P.H., Joins as Cancer Prevention Fellow
  • EGRP Provides Assistance To Develop Cancer Epidemiology Consortia
  • EGRP Funding Opportunities
    • Development, Application, and Evaluation of Prediction Models for Cancer Risk and Prognosis PAs
    • Small Grants Program for Cancer Epidemiology PAR
    • Epigenetic Approaches in Cancer Epidemiology PAs
    • Occupational Safety and Health Research PAs
    • Pilot Studies in Pancreatic Cancer PAs
    • Research on Malignancies in the Context of HIV/AIDS PAs
    • Studies of Energy Balance and Cancer in Humans PAs
    • Exfoliated Cells, Bioactive Food Components, and Cancer PAs
    • Small Business Grants (SBIR: R43/44, STTR: R41/42)
  • Other NIH and NCI Funding Opportunities
    • NIH Director’s New Innovator Award Program (DP2) RFA
    • NIH Roadmap Initiative on Epigenetics RFAs
    • NCI Innovative Molecular Analysis Technologies (IMAT) Program RFAs
    • Institutional Clinical and Translational Science Award RFA
  • Grantsmanship
    • Step-by-Step Help on Preparing Progress Reports and Final Reports With EGRP
    • NIH Data Sharing Policy In Effect for Genome-Wide Association Studies (GWAS)
    • NIH Issues Revised Policy on Enhancing Public Access to Archived Publications From NIH-Funded Research
    • Grant Applications Must Tie to Funding Opportunity Announcements
    • Paper Notification of Notice of Awards Stops
    • NIH Summarizes Policy on Late Grant Applications
    • Standing NIH Study Section Members Offered Modified Grant Application Submission, Referral, and Review
    • NIH Issues New Application Forms: Relinquishing Grant, Noncompeting Continuation Progress Report
    • NIH Web Site Showcases Small Business Technologies and Products for Potential Partners, Investors, and Licensees
  • Meetings
    • NIH Regional Seminars on Funding and Grants Administration Set for San Antonio in March, Chicago in June
    • NIH Small Business Grants Conference Set for Atlanta, July 22-23, 2008
  • EGRP-Supported Research Resources
    • Long Island Geographic Information System (GIS) Available for Breast Cancer, Other Disease Research
    • Breast and Colon Cancer Family Registries (CFRs)
    • Cancer Genetics Network (CGN)

 News Flash, January 11, 2008

EGRP Announces Appointments of Two New Branch Chiefs

NCI’s Epidemiology and Genetics Research Program (EGRP) has two new Branch Chiefs. Britt Reid, D.D.S., Ph.D., has been named to head the Modifiable Risk Factors Branch (MRFB) and Mukesh Verma, Ph.D., has been named to head the Methods and Technologies Branch (MTB). These appointments are part of last year’s reorganization of EGRP which included changing from a two-branch to a four-branch structure. Learn more about Drs. Reid and Verma and these appointments.


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11 Jul 2008
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