EGRP News Flash - December 14, 2011

NIH Announces Five Requests for Applications on Metabolomics

The National Institutes of Health (NIH) has announced five Requests for Applications (RFA) inviting proposals to increase metabolomics research capacity. The RFAs are funded through the NIH Common Fund which supports cross-cutting, trans-NIH programs.

Metabolomics is the study of low molecular weight molecules or metabolites found within cells and biological systems. The metabolome is a measure of the output of biological pathways and, as such, is often considered more representative of the functional state of a cell than other 'omics measures such as genomics or proteomics.

The five RFAs are for:

  1. Technology Development to Enable Large-Scale Metabolomics Analysis - Research Project Grant (R01) - This Funding Opportunity Announcement (FOA) is to support the development of novel technologies for metabolomics research in an effort to address current limitations in the field. The focus is on technological solutions for increasing the number, quantitative accuracy, specificity, and throughput of molecular identification; increasing the identification of specific classes of metabolites including lipids and non-polar molecules; increasing the ability to measure more unique chemical entities including isomers and enantiomers; and decreasing sample volume requirements, costs, and time of making accurate metabolomics measurements. Improvements are sought in sample preparation and handling, detector technologies and data analysis with a specific focus on metabolomics analyses. This FOA is administered by the National Institute of Environmental Health Sciences (NIEHS).

    Letters of Intent are due December 31, 2011. The application deadline is January 31, 2012, by 5 p.m. local time of the applicant organization.

    NIH Guide for Grants and Contracts: RFA-RM-11-019External Web Site Policy

  2. Development of Courses or Workshops in Metabolomics - Education Projects (R25) - Proposals are invited to support the development of innovative courses or workshops to educate students and investigators who wish to receive training in the field of metabolomics. The ultimate goal of these programs is to prepare investigators to advance the use of metabolomics in translational research and to support highly interdisciplinary teams that are conducting metabolomic studies. This award is intended to a) support planning and implementation of new workshops or courses in the varied disciplines needed for metabolomics or b) support the expansion of existing workshops or educational courses in metabolomics. This FOA is administered by the National Institute of General Medical Sciences (NIGMS).

    Letters of Intent are due December 31, 2011. The application deadline is January 31, 2012, by 5 p.m. local time of the applicant organization.

    NIH Guide for Grants and Contracts: RFA-RM-11-018External Web Site Policy

  3. Metabolomics Data Repository and Coordinating Center (DRCC) - Research Project Cooperative Agreement (U01) - This program is to provide a coordinating center and data repository for the accompanying metabolomics FOAs and metabolomics research community. One goal of the Data Repository Coordinating Center (DRCC) is to enhance metabolomics research by broadly disseminating data to researchers across the metabolomics community. Therefore, the repository will store published primary data for examination and analysis with high performance computation methods in a cloud computing environment. It will help develop the necessary tools to allow access to data and available analytical tools. The Center will also contribute to the coordination of domestic and international metabolomics efforts. This FOA is administered by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

    Letters of Intent are due January 15, 2012. Applications are due February 15, 2012, by 5 p.m. local time of the applicant organization.

    NIH Guide for Grants and Contracts: RFA-RM-11-020External Web Site Policy

  4. Regional Comprehensive Metabolomics Resource Cores (RCMRC) - Resource-Related Research Projects - Cooperative Agreements (U24) - This FOA invites cooperative agreement applications to establish Regional Comprehensive Metabolomics Resource Cores (RCMRC) to increase the national capacity for utilizing metabolomics in biomedical research. To facilitate the biological and clinical application of metabolomics, technology service cores, pilot/feasibility projects, training activities, and outreach activities will be supported. This FOA is administered by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

    Letters of Intent are due January 13, 2012, and January 15, 2013. The application deadlines are February 15, 2012, and February 15, 2013, by 5 p.m. local time of the applicant organization.

    NIH Guide for Grants and Contracts: RFA-RM-11-016External Web Site Policy

  5. Mentored Research Scientists Development Award in Metabolomics - Mentored Research Scientist Development Award (K01) - It is critical to have highly trained individuals who understand the field of metabolomics and can work and communicate with clinicians and other health professionals to perform, analyze, and interpret the data obtained from metabolomic studies. This award will provide salary and research support for a sustained period of protected time (3 to 5 years) for postdoctoral and clinical fellows or investigators who meet the definition of an NIH New Investigator to pursue intensive research training in the field of metabolomics under the guidance of an experienced mentor who has an established research record in metabolomics. This FOA is administered by the National Institute of General Medical Sciences (NIGMS).

    The application deadline is January 31, 2012, by 5 p.m. local time of the applicant organization.

    NIH Guide for Grants and Contracts: RFA-RM-11-017External Web Site Policy

For cancer epidemiology questions related to the RFAs described above, contact EGRP's Mukesh Verma, Ph.D., Chief, Methods and Technologies Branch.

Learn more about the NIH Common Fund InitiativeExternal Web Site Policy.

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