Breast and Colon Cancer Family Registries
For Research Collaborators: Initiating Collaborative Studies
The Cancer Family Registries (CFR) are designed to encourage international collaborative research. An Application and Review Process is available to investigators in the scientific community who wish to undertake collaborative research projects using CFR resources, i.e. data and biospecimen material. Investigators may apply to one or both Registries (Breast CFR and/or Colon CFR). The following documents provide an overview of the process for each registry:
Breast-CFR Review Documents:
- Breast CFR Summary of Review Process
- B-CFR Review Flow Chart for General Applications
- B-CFR Review Flow Chart for Data Only Applications
Colon-CFR Review Documents:
More information on the available data and biospecimens available from the CFRs as well as the methods used to recruit participants and collect these materials can be found in the descriptive manuscripts cited below. Questionnaires and data dictionaries used by the CFR centers can be found on the CFR Informatics Support Center website hosted by Research Triangle Institute.
Breast-CFR Descriptive Manuscripts:
- Neuhausen SL, Ozcelik H, Southey MC, John EM, Godwin AK, Chung W, Iriondo-Perez J, Miron A, Santella RM, Whittemore A, Andrulis IL, Buys SS, Daly MB, Hopper JL, Seminara D, Senie RT, Terry MB; Breast Cancer Family Registry. BRCA1 and BRCA2 mutation carriers in the Breast Cancer Family Registry: an open resource for collaborative research. Breast Cancer Res Treat. 2008 Aug 14 [Epub ahead of print].
- John EM, Hopper JL, Beck JC, Knight JA, Neuhausen SL, Senie RT, Ziogas A, Andrulis IL, Anton-Culver H, Boyd N, Buys SS, Daly MB, O'Malley FP, Santella RM, Southey MC, Venne VL, Venter DJ, West DW, Whittemore AS, Seminara D. The Breast Cancer Family Registry (Breast CFR): an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer. Breast Cancer Res 2004;6(4):R375-89.
Colon-CFR Descriptive Manuscript:
- Newcomb PA, Baron J, Cotterchio M, Gallinger S, Grove J, Haile R, Hall D, Hopper JL, Jass J, Le Marchand L, Lindor N, Potter JD, Templeton AS, Seminara D, Thibodeau S for the Colon Cancer Family Registry. Colon Cancer Family Registry: An International Resource for Studies of the Genetic Epidemiology of Colon Cancer. Cancer Epidemiol Biomarkers Prev 2007 Nov;16(11):2331-2343.
Our Online Application Tracking System is temporarily unavailable due to a transition of the CFRs Informatics Support Center. To initiate new collaborative studies please contact Ms. Valeria Rodriguez (rodrvale@mail.nih.gov) and CC Dr. Michael Burgio (burgiom@mail.nih.gov) for application forms and instructions.
For further information concerning CFR collaborations, including inquiries about the review process or available resources, please contact Sheri Dixon Schully, Ph.D., (301-594-7347) or Michael Burgio, Ph.D., 301-594-3424).
