2007 Cohort Consortium Annual Meeting Agenda

Wednesday, Nov. 14, 2007 Topic
7:00 a.m. – 8:00 a.m. Registration
8:00 a.m. – 8:55 a.m. WORKSHOP OVERVIEW
Moderator: Patricia Hartge, Sc.D., M.A., Chair, NCI Cohort Consortium

Welcome
John E. Niederhuber, M.D.
Director, National Cancer Institute

Introductions, Accomplishments and Opportunities
Patricia Hartge, Sc.D., M.A.
Deputy Director, Epidemiology and Biostatistics Program
Division of Cancer Epidemiology & Genetics
National Cancer Institute

Consortial Power and GWAS in 2007
Joseph F. Fraumeni, Jr., M.D.
Director, Division of Cancer Epidemiology and Genetics
National Cancer Institute

Current Consortium Membership
Nonye Harvey, M.P.H.
Coordinator, NCI Cohort Consortium
Program Analyst, Epidemiology and Genomics Research Program
Division of Cancer Control and Population Sciences
National Cancer Institute

NCI Update and Perspectives
Robert T. Croyle, Ph.D.
Director, Division of Cancer Control and Population Sciences
National Cancer Institute

Discussion

8:55 a.m. – 9:50 a.m. ADVANCES IN PROSTATE CANCER FROM BPC3 &a.m.p; CGEMS
Moderator: Michael Thun, M.D.

Highlights of the 8q24 Story and Contributions from CGEMS
Stephen Chanock, M.D.
Director, Core Genotyping Facility Advanced Technology Center
National Cancer Institute

BPC3 Contributions
Fredrick Schumacher, Ph.D.
Research Fellow, Department of Epidemiology and Biostatistics
Harvard School of Public Health

Genotyping Issues & Potential Relevance of 8q24 to Other Cancers
Christopher Haiman, Sc.D.
Assistant Professor, Zikha Neurogenetic Institute
Southern California Environmental Health Sciences Center
University of Southern California

New Directions
Richard B. Hayes, D.D.S., Ph.D.
Senior Investigator, Occupational and Environmental Epidemiology Branch
Division of Cancer Epidemiology and Genetics
National Cancer Institute

Discussion

9:50 a.m. – 10:10 a.m. Break
10:10 – 11:05 a.m. ADVANCES IN BREAST CANCER FROM BPC3 &a.m.p; CGEMS
Moderator: Robert Hoover, M.D., Sc.D.

Breast Cancer and GWAS: Findings and Directions in CGEMS
Peter Kraft, Ph.D.
Assistant Professor
Harvard School of Public Health

BPC3 Results and Lessons to Date
David Cox, M.S., Ph.D.
Instructor, Progra.m. in Molecular and Genetic Epidemiology
Harvard School of Public Health

Future Directions in BPC3
Heather Feigelson, Ph.D.
Director, Genetic Epidemiology, Epidemiology & Surveillance Research
American Cancer Society

Multiethnic Studies
Brian Henderson, M.D.
Dean, Keck School of Medicine
University of Southern California

Discussion

11:05 a.m. – 12:00 p.m. LESS COMMON CANCERS IN COHORT CONSORTIUM STUDIES
Moderator: Kathy Helzlsouer, M.D., M.H.S.

PanScan – Genome-wide Scan in Pancreatic Cancer
Rachael Stolzenberg-Solomon, Ph.D., M.P.H.
Investigator, Nutritional Epidemiology Branch
Division of Cancer Epidemiology and Genetics
National Cancer Institute

Charles Fuchs, M.D., M.P.H.
Associate Professor of Medicine, Medical Oncology-GCC
Dana-Farber Cancer Institute

Multiple Myeloma
Graham Colditz, MBBS, Dr.P.H., M.D.
Associate Director, Prevention and Control
Siteman Cancer Center
Washington University School of Medicine

Update on Vita.m.in D
Virginia Hartmuller, Ph.D., R.D.
Acting Branch Chief, Epidemiology and Genomics Research Program
Division of Cancer Control & Population Sciences
National Cancer Institute

Coming Together over Vita.m.in D – Study Design and Other Issues
Lisa Gallicchio, Ph.D.
Prevention and Research Center
The Weinberg Center for Women's Health and Medicine
Mercy Medical Center

12:00 p.m. – 1:00 p.m. Working Lunch
1:00 p.m. – 2:25 p.m. CONSORTIUM PRACTICES AND CHALLENGES
Moderators: Anne Zeleniuch-Jacquotte, M.D.

Debbie Winn, Ph.D.
Acting Associate Director
Epidemiology & Genomics Research Program
Division of Cancer Control &a.m.p; Population Sciences
National Cancer Institute

Proposal Review Process
Anne Zeleniuch-Jacquotte, M.D.
Associate Professor, Environmental Medicine
New York University School of Medicine

Role in Genome-wide Association Studies
Michael Thun, M.D.
Vice President, Epidemiology and Surveillance Research
American Cancer Society

Robert Hoover, M.D., Sc.D.
Director, Epidemiology and Biostatistics Program
Division of Cancer Epidemiology and Genetics
National Cancer Institute

Working Group Report and Funding Options
Scott Rogers, M.P.H.
Program Analyst, Epidemiology and Genomics Research Program
Division of Cancer Control & Population Sciences
National Cancer Institute

James Cerhan, M.D., Ph.D.
Professor of Epidemiology, Health Sciences Research
Mayo Clinic Collegeof Medicine

IRB Lessons
Robert Hoover, M.D., Sc.D.
Director, Epidemiology and Biostatistics Program
Division of Cancer Epidemiology and Genetics
National Cancer Institute

Discussion

2:25 p.m. – 2:45 p.m. Break
2:45 p.m. – 3:40 p.m. MEETING METHODOLOGIC CHALLENGES
Moderator: Julie Palmer, Sc.D., Professor of Epidemiology, Slone Epidemiology Center, Boston University

Case-Cohort versus Nested Case-Control Approaches within Cohort Studies
Clarice Weinberg, Ph.D.
Chief, Biostatistics Branch
National Institute of Environmental Health Sciences
National Institutes of Health

A New Method of Assessing Dietary Intake in Epidemiologic Studies
Arthur Schatzkin, M.D., Dr.P.H.
Chief, Nutrition Epidemiology Branch
Division of Cancer Epidemiology and Genetics
National Cancer Institute

Amy Subar, Ph.D., M.P.H., R.D.
Research Nutritionist, Risk Factor Monitoring and Methods Branch
Applied Research Program
National Cancer Institute

Whole Genome a.m.plification of Buccal Cell DNA – Recent Findings
Montserrat Garcia-Closas, M.D., Dr.P.H.
Investigator, Hormonal and Reproductive Epidemiology Branch
Division of Cancer Epidemiology and Genetics
National Cancer Institute

Use of Medicaid/Medicare Databases for Ascertainment of Non-Cancer Outcomes
James Cerhan, M.D., Ph.D.
Professor of Epidemiology, Health Sciences Research
Mayo Clinic College of Medicine

Discussion

3:40 p.m. – 4:40 p.m. IDEAS FOR NEW PROJECTS
Moderator: James Cerhan, M.D., Ph.D.

Stomach Cancer and Alcohol
Neal Freedman, D., Ph.D., M.P.H.
Nutrition Epidemiology Branch
Division of Cancer Epidemiology and Genetics
National Cancer Institute

NHL & Cytokines, Telomere Length, Genes
Presented by James Cerhan, M.D., Ph.D.
For Nat Rothman, M.D., Division of Cancer Epidemiology and Genetics, National Cancer Institute

Possible Collaboration with Interlymph
Paolo Boffetta
Cluster Coordinator, Lifestyle, Environment, and Cancer Department
International Agency for Research on Cancer

Viruses, Immune Response, Genomic Variation and Brain Tumor Risk
Beatrice Malmer, M.D., Ph.D.
Associate Professor, Department of Radiation Sciences
Umea University

Upper Gastrointestinal Cancers
Kathy Helzlsouer, M.D., M.H.S.
Medical Director, Prevention and Research Center
Weinberg Center for Women's Health & Medicine, Mercy Medical Center

Biomarkers of Systemic Infla.m.mation & Risk of Endometrial Cancer
Xiao Ou Shu, M.D., Ph.D.
Professor, Internal Medicine and Public Health
Vanderbilt University

Circulating Vitamin D and Breast and Colorectal Cancer
Stephanie Smith-Warner, Ph.D.
Assistant Professor, Nutritional Epidemiology
Harvard School of Public Health

Other Ideas from Floor

4:40 p.m. – 5:00 p.m. WORKSHOP RECOMMENDATIONS
Moderator: Patricia Hartge, Sc.D., M.A.

Summary of Recommendations
Cohort Consortium Secretariat (new and outgoing)

Workshop Evaluation, Plans for 2008
Nonye Harvey, M.P.H.

5:00 p.m. Adjourn

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