| Thursday, May 4, 2006 |
 |
| 7:15 a.m. – 8:00 a.m. |
Registration |
| 8:00 a.m. – 8:30 a.m. |
SESSION 1: Introduction From NCI |
| 8:00 a.m. |
Welcome and Introduction
Edward Trapido, Sc.D.
Epidemiology
and Genetics Research Program, National Cancer Institute |
| 8:15 a.m. |
Overview and Meeting Objectives
J. Fernando Arena, M.D.,
Ph.D.
Epidemiology and Genetics Research Program, National Cancer Institute |
| 8:30 a.m. – 9:40 a.m. |
SESSION 2: Assessing Human Genetic Variation and Environmental
Variation To Investigate Disease Phenotypes
Moderator: Timothy Rebbeck,
Ph.D. University of Pennsylvania |
| 8:30 a.m. |
Dissecting Racial and Ethnic Differences
Neil Risch, Ph.D.
University of California at San Francisco |
| 9:20 a.m. – 9:40 a.m. |
Discussion/Questions |
| 9:40 a.m. – 12:15 p.m. |
SESSION 3: Admixture
Moderator: Guilherme Suarez-Kurtz,
M.D., Ph.D. Instituo Nacional de Cancer (INCA) Brazilian National Cancer
Institute |
| 9:40 a.m. |
What’s in a Word? Models and Realities Underlying
the Term “Admixture”
Joanna Mountain, Ph.D.
Stanford University |
| 10:00 a.m. – 10:30 a.m. |
Break |
| 10:30 a.m. |
The African Diaspora
John Thornton, Ph.D., and Linda M.
Heywood, Ph.D.
Boston University |
| 10:50 a.m. |
Genetic Consequences of the African Diaspora
Rick Kittles,
Ph.D.
The Ohio State University |
| 11:10 a.m. |
Charting the Iberian Peninsula Contribution to Ancestry
in Latin America
Angel Carracedo, Ph.D.
Institute of Legal Medicine,
University of Santiago de Compostela
Antonio Salas, Ph.D.
Molecular Medicine
Group, IML Genetics, University of Santiago de Compostela |
| 11:30 a.m |
Moving Beyond Continental Admixture: What Can Be Said
About Intracontinental Genetic Contributions
Mark Shriver, Ph.D.
The
Pennsylvania State University |
| 11:50 a.m. – 12:15 p.m. |
Discussion/Questions |
| 12:15 p.m. – 2:00 p.m. |
Lunch (On Your Own) |
| 2:00 p.m. – 3:40 p.m. |
SESSION 4: Admixture Surveys in Latin American Populations
Within the American Continents
Moderator: Eduardo Tarazona Santos, Ph.D.
Federal University of Minas Gerais, Brazil |
| 2:00 p.m. |
Admixture in Hispanic/Latino Populations: Distribution
of Ancestral Population Contributions in the Continental United States
Ranajit Chakraborty, Ph.D.
University of Cincinnati |
| 2:20 p.m. |
Patterns of Genetic Variation in Indigenous Populations
from Mexico, Central America, and the Caribbean
Carolina Bonilla, Ph.D.
The Ohio State University |
| 2:40 p.m. |
Patterns of Genetic Variation in Indigenous Populations
From South America
Andre Ruiz Linares, Ph.D.
University College, London |
| 3:00 p.m. |
From “Mestizo” to “Metis”:
Insights and Perspectives on Admixture in Mexico and Canada
Esteban Parra, Ph.D.
University of Toronto, Canada |
| 3:20 p.m. – 3:40 p.m. |
Discussion/Questions |
| 3:40 p.m. – 4:00 p.m. |
Break |
| 4:00 p.m. – 5:20 p.m. |
SESSION 5: Risk and Risk Factors for Cancer in Hispanic/Latino
Populations
Moderator: Esther John, Ph.D. Northern California Cancer
Center |
| 4:00 p.m. |
Cancer Incidence and Mortality Trends in Hispanic/Latino
Populations in the Americas
Barry Miller, Ph.D.
Surveillance Research
Program, National Cancer Institute |
| 4:20 p.m. |
Genetic Epidemiology: The Value of Population Differences
Maria Elena Martinez, Ph.D.
University of Arizona |
| 4:40 p.m. |
Cancer Epidemiological Studies in Latin Americans
Veronica Wendy Setiawan, Ph.D.
University of Southern California |
| 5:00 p.m. |
Admixture Mapping for Breast Cancer in Latinas
Elad Ziv, M.D.
University of California at San Francisco |
| 5:20 p.m. |
Polymorphisms of Inflammatory Cytokines as Markers
of Ancestry in the Americas
Pelayo Correa, M.D.
Vanderbilt |
| 5:20 p.m. – 5:40 p.m. |
Discussion/Questions |
| 5:40 p.m. |
Adjournment |
| Friday, May 5, 2006 |
| 7:15 a.m. – 8:00 a.m. |
Registration |
| 8:00 a.m. – 8:55 a.m. |
SESSION 6: The Power of Connecting
Networks for Common Purposes: An Experience To Be Extended to Latin Americans
Populations
Moderator: Victoria Cortessis, Ph.D. University of Southern
California |
| 8:00 a.m. |
Potential of Network Collaborations
Amelie G.
Ramirez, Dr.P.H.
Baylor College of Medicine |
| 8:20 a.m. |
A Network of Investigator Networks in Human
Genome Epidemiology
Teri Manolio, M.D., Ph.D.
National Heart, Lung, and
Blood Institute |
| 8:40 a.m. – 8:55 a.m. |
Discussion/Questions |
| 8:55 a.m. – 10:35 a.m. |
SESSION 7: Issues in Study
Design and Analysis
Moderator: Daniela Seminara, Ph.D. Epidemiology and
Genetics Research Program, National Cancer Institute |
| 8:55 a.m. |
Pattern of Linkage Disequilibrium and Association
Studies in Humans
Jeffrey Wall, Ph.D.
University of Southern California |
| 9:15 a.m. |
Population Stratification Confounds Genetic
Association Studies Among Latinos
Hua Tang, Ph.D.
Fred Hutchinson Cancer
Center, Seattle |
| 9:35 a.m. |
Genomic Regions Exhibiting Positive Selection
Identified From Dense Genotype Data
Joshua Akey, Ph.D.
University of
Washington |
| 9:55 a.m. |
Tag Single Nucleotide Polymorphisms (SNPs) in
Admixed Populations
Eduardo Tarazona Santos, Ph.D.
Federal University
of Minas Gerais, Brazil |
| 10:15 a.m. – 10:35 a.m. |
Discussion/Questions |
| 10:35 a.m. – 11:00 a.m. |
Break |
| 11:00 a.m. – 12:30 p.m. |
SESSION 8: Specific Topic
Overviews
Moderator: Pelayo Correa, M.D. Vanderbilt University |
| 11:00 a.m. |
Pharmacogenetics Research Network (PgRN)
Howard
L. McLeod, Pharm.D.
Washington University School of Medicine |
| 11:30 a.m. |
Advancement of Methodologies and Technologies
Stephen Chanock, M.D.
Core Genotyping Facility, Division of Cancer Epidemiology
and Genetics, National Cancer Institute |
| 12:00 p.m. |
Ethics: An Overview
Pilar Ossorio, J.D., Ph.D.
University of Wisconsin |
| 12:30 p.m. – 2:00 p.m. |
Lunch (On Your Own) |
| 2:00 p.m. – 5:00 p.m. |
PANEL DISCUSSION: Overall
Summary of What Was Discussed in Each Topic During the Previous Day
Moderator:
Duncan Thomas, Ph.D. University of Southern California |
| 2:00 p.m. – 2:30 p.m. |
Methods: Discussion: 15 min.
Paul McKeigue, Ph.D.
University College Dublin |
| 2:30 p.m. – 3:00 p.m. |
Cancer Epidemiology: Discussion: 15 min
Debbie
Winn, Ph.D.
Epidemiology and Genetics Research Program, National Cancer
Institute |
| 3:00 p.m. – 3:30 p.m. |
Indigenous Populations: Discussion: 15 min.
Jeffrey
Reading, Ph.D.
Institute of Aboriginal Peoples’ Health, Canadian
Institutes of Health Research |
| 3:30 p.m. – 4:00 p.m. |
Break |
| 4:00 p.m. – 4:30 p.m. |
Admixture: Discussion: 15 min.
Mark Shriver, Ph.D.
The Pennsylvania State University |
| 4:30 p.m. – 5:00 p.m. |
Ethics: Discussion:
15 min.
Vivian Ota Wang, Ph.D.
ELSI Research Program, National Human Genome Research Institute |
| 5:00 p.m. – 5:15 p.m. |
Closing Remarks |
| 5:15 p.m. |
Adjournment |
