Research Highlights from EGRP Grantees - 2013
EGRP staff nominated and voted for manuscripts published in 2013 by EGRP grantees that were deemed to have the greatest potential scientific and/or public health impact. The final 10 selections for EGRP's 2013 Research Highlights are presented below.
EGRP funds research in human populations to understand determinants of cancer occurrence and outcomes. EGRP is the largest funder of cancer epidemiology grants nationally and worldwide, supporting more than 400 grants and cooperative agreements annually. View a full list of active EGRP grants.
The research featured below was funded in full or in part by EGRP:
Liu Y, Colditz GA, Rosner B, Berkey CS, Collins LC, Schnitt SJ, et al. Alcohol intake between menarche and first pregnancy: a prospective study of breast cancer risk. J Natl Cancer Inst. 2013 Oct 16;105(20):1571-8.
This research was funded in part by EGRP grants to Walter Willett, M.D., M.P.H., Dr.P.H., of Harvard School of Public Health.
Kroenke CH, Kwan ML, Sweeney C, Castillo A, Caan BJ. High- and low-fat dairy intake, recurrence, and mortality after breast cancer diagnosis. J Natl Cancer Inst. 2013 May 1;105(9):616-23.
This research was funded by an EGRP grant to Bette Caan, Dr.P.H., of the Kaiser Permanente Division of Research.
Biro FM, Greenspan LC, Galvez MP, Pinney SM, Teitelbaum S, Windham GC, et al. Onset of breast development in a longitudinal cohort. Pediatrics. 2013 Dec;132(6):1019-27.
This research was funded as part of the Breast Cancer and the Environment Research Program (BCERP), a consortium supported by EGRP and the National Institute of Environmental and Health Sciences (NIEHS). Learn more about the BCERP.
Li CI, Daling JR, Tang MT, Haugen KL, Porter PL, Malone KE. Use of antihypertensive medications and breast cancer risk among women aged 55 to 74 years. JAMA Intern Med. 2013 Sep 23;173(17):1629-37.
The research was supported in part by an EGRP grant to Christopher Li, M.D., Ph.D., of the Fred Hutchinson Cancer Research Center.
Bao Y, Han J, Hu FB, Giovannucci EL, Stampfer MJ, Willett WC, et al. Association of nut consumption with total and cause-specific mortality. N Engl J Med. 2013 Nov 21;369(21):2001-11.
This research was funded in part by grants to Meir J. Stampfer, Dr.P.H., M.D., of Brigham and Women's Hospital and Charles S. Fuchs of the Dana-Farber Cancer Institute.
Berndt SI, Skibola CF, Joseph V, Camp NJ, Nieters A, Wang Z, et al. Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. Nat Genet. 2013 Aug;45(8):868-76.
This research was funded in part by grants to James Cerhan, M.D., Ph.D., of the Mayo Clinic, Rochester; Chistine Skibola, Ph.D., of the University of Alabama, Birmingham; Nicola J. Camp, Ph.D., of the University of Utah; Brenda M. Birmann, Sc.D., of Brigham and Women's Hospital; and Susan L. Slager, Ph.D., of the Mayo Clinic, Rochester.
Miglioretti DL, Johnson E, Williams A, Greenlee RT, Weinmann S, Solberg LI, et al. The use of computed tomography in pediatrics and the associated radiation exposure and estimated cancer risk. JAMA Pediatr. 2013 Aug 1;167(8):700-7.
This research was funded in part by an EGRP grant to Rebecca Smith-Bindman, M.D., of the University of California, San Francisco.
Brenner DR, Brennan P, Boffetta P, Amos CI, Spitz MR, Chen C, et al. Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls. Hum Genet. 2013 May;132(5):579-89.
This research was funded in part by grants to Christopher I. Amos, Ph.D., of Dartmouth College and Margaret R. Spitz, M.D., M.P.H., of Baylor College of Medicine.
Pharoah PD, Tsai YY, Ramus SJ, Phelan CM, Goode EL, Lawrenson K, et al. GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat Genet. 2013 Apr;45(4):362-70, 370e1-2.
This research was funded in part by grants to Ellen L. Goode, Ph.D., of the Mayo Clinic, Rochester; Catherine Phelan, Ph.D., M.D., M.M.S, and Thomas A. Sellers, Ph.D., of the H. Lee Moffitt Cancer Center and Research Institute; and Wei Zheng, Ph.D., M.D., M.P.H., of Vanderbilt University Medical Center.
Skeeles LE, Fleming JL, Mahler KL, Toland AE. The impact of 3'UTR variants on differential expression of candidate cancer susceptibility genes. PLoS One. 2013;8(3):e58609.
This research was funded in part by an EGRP grant to Amanda E. Toland, Ph.D., of The Ohio State University.