Cohorts and Consortia Team
The Cohorts and Consortia Team (CC) resides in the Epidemiology and Genomics Research Program's (EGRP) Office of the Associate Director (OAD). The Team is tasked with the scientific and programmatic stewardship and coordination of the cancer epidemiology cohorts and cancer epidemiology consortia supported by EGRP. This includes the planning, design, and conduct of cohort- and consortia-related initiatives and workshops; design and implementation of informatics tools and databases to facilitate cohorts and consortia research; synthesis, integration, and publication of consortia and cohort findings and related literature reviews; and development and promotion of best practices for interdisciplinary and translational collaborative research.
The CC Team's mission is to foster, coordinate, and evaluate collaborative research based on cancer epidemiology cohorts and consortia. This includes the support of research resources and infrastructure to facilitate and maximize the scientific potential of cancer epidemiology research in the areas of focus of EGRP's Branches.
The CC Team's mission also includes disseminating findings from Team-supported research to the public, health care professionals, scientists engaged in cancer control, and the public health community.
Cohorts and Consortia Activities and Resources
EGRP has been engaged in collaborative efforts to promote consortia-based initiatives and activities for some time across multiple branches of the program. The commitment to supporting cancer epidemiology cohorts also is long-term. Establishing the CC Team is a reflection of this commitment.
The CC Team expands EGRP's efforts through a variety of initiatives addressing the establishment of infrastructure, promotion of large-scale data integration within the framework of epidemiology, and interdisciplinary initiatives promoting the acceleration of the translational pipeline. Examples include:
- Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (U01, PAR-14-160) - expires March 11, 2017, unless reissued
- Genetic Associations and Mechanisms in Oncology (GAME-ON) Initiative
- OncoArray Network
- Collaborative cancer epidemiology in the 21st century: the model of cancer consortia. Burgio MR, Ioannidis JP, Kaminski BM, Derycke E, Rogers S, Khoury MJ, Seminara D. Cancer Epidemiol Biomarkers Prev. 2013 Dec;22(12):2148-60.
- Transforming epidemiology for 21st century medicine and public health. Khoury MJ, Lam TK, Ioannidis JP, Hartge P, Spitz MR, Buring JE, Chanock SJ, Croyle RT, Goddard KA, Ginsburg GS, Herceg Z, Hiatt RA, Hoover RN, Hunter DJ, Kramer BS, Lauer MS, Meyerhardt JA, Olopade OI, Palmer JR, Sellers TA, Seminara D, Ransohoff DF, Rebbeck TR, Tourassi G, Winn DM, Zauber A, Schully SD. Cancer Epidemiol Biomarkers Prev. 2013 Apr;22(4):508-16.
- Leveraging epidemiology and clinical studies of cancer outcomes: recommendations and opportunities for translational research. Elena JW, Travis LB, Simonds NI, Ambrosone CB, Ballard-Barbash R, Bhatia S, Cerhan JR, Hartge P, Heist RS, Kushi LH, Lash TL, Morton LM, Onel K, Pierce JP, Robison LL, Rowland JH, Schrag D, Sellers TA, Seminara D, Shu XO, Thomas NE, Ulrich CM, Freedman AN. J Natl Cancer Inst. 2013 Jan 16;105(2):85-94.
- Frontiers in cancer epidemiology: a challenge to the research community from the Epidemiology and Genomics Research Program at the National Cancer Institute. Khoury MJ, Freedman AN, Gillanders EM, Harvey CE, Kaefer C, Reid BC, Rogers S, Schully SD, Seminara D, Verma M. Cancer Epidemiol Biomarkers Prev. 2012 Jul;21(7):999-1001.
- Recommendations and proposed guidelines for assessing the cumulative evidence on joint effects of genes and environments on cancer occurrence in humans. Boffetta P, Winn DM, Ioannidis JP, Thomas DC, Little J, Smith GD, Cogliano VJ, Hecht SS, Seminara D, Vineis P, Khoury MJ. Int J Epidemiol. 2012 Jun;41(3):686-704.
- Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration. Janssens AC, Ioannidis JP, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J, Gwinn M, Hlatky MA, Janes H, Kraft P, Melillo S, O'Donnell CJ, Pencina MJ, Ransohoff D, Schully SD, Seminara D, Winn DM, Wright CF, van Duijn CM, Little J, Khoury MJ. J Clin Epidemiol. 2011 Aug;64(8):e1-e22.
- Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009). Boffetta P, Colditz GA, Potter JD, Kolonel L, Robson PJ, Malekzadeh R, Seminara D, Goode EL, Yoo KY, Demers P, Gallagher R, Prentice R, Yasui Y, O'Doherty K, Petersen GM, Ulrich CM, Csizmadi I, Amankwah EK, Brockton NT, Kopciuk K, McGregor SE, Kelemen LE. Cancer Causes Control. 2011 Mar;22(3):463-8.
- Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases. Khoury MJ, Bertram L, Boffetta P, Butterworth AS, Chanock SJ, Dolan SM, Fortier I, Garcia-Closas M, Gwinn M, Higgins JP, Janssens AC, Ostell J, Owen RP, Pagon RA, Rebbeck TR, Rothman N, Bernstein JL, Burton PR, Campbell H, Chockalingam A, Furberg H, Little J, O'Brien TR, Seminara D, Vineis P, Winn DM, Yu W, Ioannidis JP. Am J Epidemiol. 2009 Aug 1;170(3):269-79.
- The emergence of networks in human genome epidemiology: challenges and opportunities. Seminara D, Khoury MJ, O'Brien TR, Manolio T, Gwinn ML, Little J, Higgins JP, Bernstein JL, Boffetta P, Bondy M, Bray MS, Brenchley PE, Buffler PA, Casas JP, Chokkalingam AP, Danesh J, Davey Smith G, Dolan S, Duncan R, Gruis NA, Hashibe M, Hunter D, Jarvelin MR, Malmer B, Maraganore DM, Newton-Bishop JA, Riboli E, Salanti G, Taioli E, Timpson N, Uitterlinden AG, Vineis P, Wareham N, Winn DM, Zimmern R, Ioannidis JP; Human Genome Epidemiology Network; Network of Investigator Networks. Epidemiology. 2007 Jan;18(1):1-8
|Name / Title / Contact Info||Interest Areas|
Seminara, Daniela, Ph.D., M.P.H.
Phone: (240) 276-6748
Dr. Seminara will be on an Intergovernment Personnel Act assignment to the Stanford Cancer Institute from June 2014 to June 2015 as a Consulting Professor in Population Sciences. During this time, Dr. Seminara can be reached via e-mail for science-related questions but will not have any grants management responsibilities or input on funding decisions.
Kennedy, Amy, Ph.D., M.P.H.
Phone: (240) 276-6723
Lane, Crystal, M.P.H., M.S.
Phone: (240) 276-6771