Knowledge Integration Team


Overview

Knowledge Integration members, from left to right: Tram Lam, Ph.D., M.P.H.; Sheri Schully, Ph.D.; and Christine Chang, M.P.H.M.

Knowledge Integration Team
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The Knowledge Integration (KI) Team resides in the Epidemiology and Genomics Research Program (EGRP)'s Office of the Associate Director (OAD). The Team is tasked with systematically integrating the rapidly accumulating knowledge base and tools for cancer epidemiology and genomics to accelerate research, evidence-based recommendations, and translation into prevention and clinical practice. It accomplishes this by creating and maintaining online information and databases, meta-research projects, and conducting systematic scientific literature reviews.

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Mission

The KI Team's mission is to develop, coordinate, and evaluate:

  • Integration of existing and new knowledge across the disciplines of cancer epidemiology and genomics;
  • Development of tools to facilitate the communication and presentation of the body of evidence on cancer epidemiology and genomics; and
  • Publication of synthesized findings to aid evidence-based clinical practices and policy recommendations.

Integral to its mission is an on-going collaboration with all EGRP staff and researchers across governmental, academic, and non-governmental institutions.

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Vision

The KI Team's vision is to foster the advancement of cancer epidemiology research across the translational continuum by systematic integration and synthesis of findings to reduce the burden of cancer.

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What is Knowledge Integration?

KI is the systematic process of combining information from many sources (and disciplines) in order to accelerate the translation of scientific discoveries into health benefits for both individuals and populations. The process involves three components:

  • Knowledge management (KM) - a continuous process of identifying, selecting, storing, curating, and tracking relevant information from multiple disciplines;
  • Knowledge synthesis (KS) - the process of applying technical methods for the systematic review of published and unpublished data using a priori rules of evidence. It may include meta-analysis, decision analysis, and modeling; and
  • Knowledge translation (KT) - the process of using synthesized information to influence policy, guideline development, practice, and research.

These three components complement one another, and in concert, inform the translational research continuum from discovery to population health impact.

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Knowledge Integration Activities and Resources

In data-intensive fields such as epidemiology, KI is an essential process to systematically identify what we know and/or don't know about cancer causes and outcomes. EGRP has a history of involvement and engagement in collaborative efforts to promote KS activities and resources across multiple branches. The creation of the KI Team is a reflection of this commitment. The Team expands EGRP's efforts through a variety of collaborations to integrate and synthesize knowledge, such as:

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Key Publications

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Contacts

Name / Title / Contact Info Interest Areas

Schully, Sheri D., Ph.D.
Knowledge Integration Team Lead

Phone: (240) 276-6936
Email: schullys@mail.nih.gov

  • Using the tools of Knowledge Integration to uncover what is known or unknown about cancer epidemiology
  • Translation of genome-based knowledge and technologies to improve population health and the use of biospecimens in research

Chang, Christine, M.P.H.
Cancer Research Training Award Fellow

Phone: (240) 276-6742
Email: christine.chang2@nih.gov

  • Cancer epidemiology
  • Modifiable risk factors and health-related behaviors
  • Communicating health information to the lay public
  • Use of GIS in public health

Clyne, Mindy, M.H.S.
Contractor, Research Associate

Email: mindy.clyne@nih.gov

  • Human genome epidemiology
  • Public health genomics
  • Cancer epidemiology
  • Database design and application for analysis and translation of genomic information

Lam, Tram K., Ph.D., M.P.H.
Program Director, Knowledge Integration Team

Phone: (240) 276-6967
Email: lamt@nih.gov

  • Using the tools of Knowledge Integration to canvas the interdisciplinary field of cancer epidemiology and advance research by synthesizing prior knowledge, incorporating new information, identifying gaps, and translating findings
  • Investigating how environmental factors influence or interact with genomic factors, and how these affect cancers and cancer outcomes

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