Boston Collaborative Drug Surveillance Program


Description

The Boston Collaborative Drug Surveillance Program (BCDSP) started in 1966 and conducted epidemiologic research to quantify the potential adverse effects of prescription drugs, utilizing in-hospital monitoring. The BCDSP also made a major contribution to the development and validation of the UK General Practice Research Database (GPRD). The BCDSP currently conducts pharmacoepidemiology studies using large automated patient databases.

The program does not appear to maintain any searchable databases.

Selected References

Etiology

Kaye JA, Meier CR, Walker AM, Jick H. Statin use, hyperlipidaemia, and the risk of breast cancerExternal Web Site Policy. Br J Cancer. 2002 May 6;86(9):1436-9.

Meier CR, Schmitz S, Jick H. Association between acetaminophen or nonsteroidal antiinflammatory drugs and risk of developing ovarian, breast, or colon cancerExternal Web Site Policy. Pharmacotherapy. 2002 Mar;22(3):303-9.

Meier CR, Derby LE, Jick SS, Jick H. Angiotensin-converting enzyme inhibitors, calcium channel blockers, and breast cancerExternal Web Site Policy. Arch Intern Med. 2000 Feb 14;160(3):349-53.

Jick H, Jick S, Derby LE, Vasilakis C, Myers MW, Meier CR. Calcium-channel blockers and risk of cancerExternal Web Site Policy. Lancet. 1997 Feb 22;349(9051):525-8.

Derby LE, Jick H. Acetaminophen and renal and bladder cancerExternal Web Site Policy. Epidemiology. 1996 Jul;7(4):358-62.

Garcia-Rodriguez LA, Huerta-Alvarez C. Reduced risk of colorectal cancer among long-term users of aspirin and nonaspirin nonsteroidal antiinflammatory drugsExternal Web Site Policy. Epidemiology. 2001 Jan;12(1):88-93.

Pedersen A. [The pill and cancer of the breast and cervix uteri]External Web Site Policy Ugeskr Laeger. 1984 Apr 2;146(14):1063-6. Danish.

Amphetamines and malignant lymphoma. A report from the Boston Collaborative Drug Surveillance ProgramExternal Web Site Policy. JAMA. 1974 Sep 9;229(11):1462-3.

Treatment/Survivorship

Bradbury BD, Lash TL, Kaye JA, Jick SS. Tamoxifen-treated breast carcinoma patients and the risk of acute myocardial infarction and newly-diagnosed anginaExternal Web Site Policy. Cancer. 2005 Mar 15;103(6):1114-21.

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