Cancer Genomic Evidence-based Medicine Knowledge Base (CancerGEM KB)
An integrated, searchable knowledge base of cancer human genome epidemiology and genomic applications in cancer care and prevention.
CDC Office of Public Health Genomics in collaboration with NCI Division of Cancer Control and Population Sciences has launched the CancerGEM KB. CancerGEM KB is an online resource for researchers, public health professionals, policy makers, and health care providers interested in the use of genomic information in cancer care and prevention. CancerGEM KB offers provides objective synthesis and timely dissemination of information on cancer human genome epidemiology (genetic associations, gene-environment interactions and gene prevalence information) and aggregated evidence on cancer genomic tests in transition to clinical and public health practice. CancerGEM KB also offers summary information on Genomic Tests through PLoS Currents Evidence on Genomic Tests, an open-access online publication featuring short summaries of evidence for the validity and utility of genetic tests.
About CancerGEM KB
CancerGEM KB is a continuously updated searchable online resource that provides access to scientific information on the use of genomic information in cancer care and prevention.
This knowledge base consists of the following database/applications:
- Cancer HuGE Literature Finder finds published articles on human genome epidemiologic research in cancer, including genetic associations and gene-environment interactions.
- Cancer GAMAdb gives cancer researchers and clinicians quick access to the latest genome-wide association studies and meta-analyses of genetic associations with cancer.
- Cancer Evidence Aggregator facilitates searching for evidence reports, systematic reviews, recommendations, and guidelines related to genetic tests and other applications of genomic technologies in cancer. Information is collected from several sources, such as the US Preventive Services Task Force, the Agency for Healthcare Research and Quality, the Evaluation of Genomic Applications in Practice and Prevention (EGAPP) project, and PLoS Currents: Evidence on Genomic Tests, and others.
- Cancer Genomic Test Finder is a curated database of cancer-related genetic tests that are in transition from development to practice. Data can be searched and sorted by disease, gene, drug, and type of test.
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