First Workshop on Cancer Epidemiology and Genomics Variation in Hispanic/Latino Populations within the American Continents

Workshop Agenda


Thursday, May 4, 2006 Topic
7:15 a.m. – 8:00 a.m. Registration
SESSION 1: Introduction From NCI
8:00 a.m. Welcome and Introduction
Edward Trapido, Sc.D.
Epidemiology and Genetics Research Program, National Cancer Institute
8:15 a.m. Overview and Meeting Objectives
J. Fernando Arena, M.D., Ph.D.
Epidemiology and Genetics Research Program, National Cancer Institute
SESSION 2: Assessing Human Genetic Variation and Environmental Variation To Investigate Disease Phenotypes
Moderator: Timothy Rebbeck, Ph.D., University of Pennsylvania
8:30 a.m. Dissecting Racial and Ethnic Differences
Neil Risch, Ph.D.
University of California at San Francisco
9:20 a.m. – 9:40 a.m. Discussion/Questions
SESSION 3: Admixture
Moderator: Guilherme Suarez-Kurtz, M.D., Ph.D., Instituo Nacional de Cancer (INCA) Brazilian National Cancer Institute
9:40 a.m. What's in a Word? Models and Realities Underlying the Term "Admixture"
Joanna Mountain, Ph.D.
Stanford University
10:00 a.m. – 10:30 a.m. Break
10:30 a.m. The African Diaspora
John Thornton, Ph.D., and Linda M. Heywood, Ph.D.
Boston University
10:50 a.m. Genetic Consequences of the African Diaspora
Rick Kittles, Ph.D.
The Ohio State University
11:10 a.m. Charting the Iberian Peninsula Contribution to Ancestry in Latin America
Angel Carracedo, Ph.D.
Institute of Legal Medicine, University of Santiago de Compostela

Antonio Salas, Ph.D.
Molecular Medicine Group, IML Genetics, University of Santiago de Compostela

11:30 a.m Moving Beyond Continental Admixture: What Can Be Said About Intracontinental Genetic Contributions
Mark Shriver, Ph.D.
The Pennsylvania State University
11:50 a.m. – 12:15 p.m. Discussion/Questions
12:15 p.m. – 2:00 p.m. Lunch (On Your Own)
SESSION 4: Admixture Surveys in Latin American Populations Within the American Continents
Moderator: Eduardo Tarazona Santos, Ph.D.
Federal University of Minas Gerais, Brazil
2:00 p.m. Admixture in Hispanic/Latino Populations: Distribution of Ancestral Population Contributions in the Continental United States
Ranajit Chakraborty, Ph.D.
University of Cincinnati
2:20 p.m. Patterns of Genetic Variation in Indigenous Populations from Mexico, Central America, and the Caribbean
Carolina Bonilla, Ph.D.
The Ohio State University
2:40 p.m. Patterns of Genetic Variation in Indigenous Populations From South America
Andre Ruiz Linares, Ph.D.
University College, London
3:00 p.m. From "Mestizo" to "Metis": Insights and Perspectives on Admixture in Mexico and Canada
Esteban Parra, Ph.D.
University of Toronto, Canada
3:20 p.m. – 3:40 p.m. Discussion/Questions
3:40 p.m. – 4:00 p.m. Break
SESSION 5: Risk and Risk Factors for Cancer in Hispanic/Latino Populations
Moderator: Esther John, Ph.D., Northern California Cancer Center
4:00 p.m. Cancer Incidence and Mortality Trends in Hispanic/Latino Populations in the Americas
Barry Miller, Ph.D.
Surveillance Research Program, National Cancer Institute
4:20 p.m. Genetic Epidemiology: The Value of Population Differences
Maria Elena Martinez, Ph.D.
University of Arizona
4:40 p.m. Cancer Epidemiological Studies in Latin Americans
Veronica Wendy Setiawan, Ph.D.
University of Southern California
5:00 p.m. Admixture Mapping for Breast Cancer in Latinas
Elad Ziv, M.D.
University of California at San Francisco
5:20 p.m. Polymorphisms of Inflammatory Cytokines as Markers of Ancestry in the Americas
Pelayo Correa, M.D.
Vanderbilt
5:20 p.m. – 5:40 p.m. Discussion/Questions
5:40 p.m. Adjournment

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Friday, May 5, 2006 Topic
7:15 a.m. – 8:00 a.m. Registration
SESSION 6: The Power of Connecting Networks for Common Purposes: An Experience To Be Extended to Latin Americans Populations
Moderator: Victoria Cortessis, Ph.D., University of Southern California
8:00 a.m. Potential of Network Collaborations
Amelie G. Ramirez, Dr.P.H.
Baylor College of Medicine
8:20 a.m. A Network of Investigator Networks in Human Genome Epidemiology
Teri Manolio, M.D., Ph.D.
National Heart, Lung, and Blood Institute
8:40 a.m. – 8:55 a.m. Discussion/Questions
SESSION 7: Issues in Study Design and Analysis
Moderator: Daniela Seminara, Ph.D., Epidemiology and Genetics Research Program, National Cancer Institute
8:55 a.m. Pattern of Linkage Disequilibrium and Association Studies in Humans
Jeffrey Wall, Ph.D.
University of Southern California
9:15 a.m. Population Stratification Confounds Genetic Association Studies Among Latinos
Hua Tang, Ph.D.
Fred Hutchinson Cancer Center, Seattle
9:35 a.m. Genomic Regions Exhibiting Positive Selection Identified From Dense Genotype Data
Joshua Akey, Ph.D.
University of Washington
9:55 a.m. Tag Single Nucleotide Polymorphisms (SNPs) in Admixed Populations
Eduardo Tarazona Santos, Ph.D.
Federal University of Minas Gerais, Brazil
10:15 a.m. – 10:35 a.m. Discussion/Questions
10:35 a.m. – 11:00 a.m. Break
SESSION 8: Specific Topic Overviews
Moderator: Pelayo Correa, M.D., Vanderbilt University
11:00 a.m. Pharmacogenetics Research Network (PgRN)
Howard L. McLeod, Pharm.D.
Washington University School of Medicine
11:30 a.m. Advancement of Methodologies and Technologies
Stephen Chanock, M.D.
Core Genotyping Facility, Division of Cancer Epidemiology and Genetics, National Cancer Institute
12:00 p.m. Ethics: An Overview
Pilar Ossorio, J.D., Ph.D.
University of Wisconsin
12:30 p.m. – 2:00 p.m. Lunch (On Your Own)
PANEL DISCUSSION: Overall Summary of What Was Discussed in Each Topic During the Previous Day
Moderator: Duncan Thomas, Ph.D., University of Southern California
2:00 p.m. – 2:30 p.m. Methods: Discussion: 15 min.
Paul McKeigue, Ph.D.
University College Dublin
2:30 p.m. – 3:00 p.m. Cancer Epidemiology: Discussion: 15 min
Debbie Winn, Ph.D.
Epidemiology and Genetics Research Program, National Cancer Institute
3:00 p.m. – 3:30 p.m. Indigenous Populations: Discussion: 15 min.
Jeffrey Reading, Ph.D.
Institute of Aboriginal Peoples' Health, Canadian Institutes of Health Research
3:30 p.m. – 4:00 p.m. Break
4:00 p.m. – 4:30 p.m. Admixture: Discussion: 15 min.
Mark Shriver, Ph.D.
The Pennsylvania State University
4:30 p.m. – 5:00 p.m. Ethics:
Discussion: 15 min.
Vivian Ota Wang, Ph.D.
ELSI Research Program, National Human Genome Research Institute
5:00 p.m. – 5:15 p.m. Closing Remarks
5:15 p.m. Adjournment

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