EGRP News Flash - September 20, 2010

New Funding Opportunity Announced: Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts

The National Cancer Institute’s (NCI) Division of Cancer Control and Population Sciences (DCCPS) published a Funding Opportunity Announcement (FOA) in the NIH Guide for Grants and Contracts inviting applications for targeted infrastructure support for core functions of cancer epidemiology cohorts (CECs) and methodological research.

Support is envisioned for two types of CECs through this FOA:

  1. A cohort of at least 10,000 study participants that is intended to examine multiple exposures and study participant characteristics, and one or multiple types of incident cancer, or
  2. A cohort of at least the same size designed to study cancer-related outcomes among persons diagnosed with cancer Cancer-related outcomes among cancer survivors include, but are not limited to, cancer recurrence, development of new primaries, survival and physical health conditions, chronic diseases related to the cancer, cancer-directed therapy, or its consequences.

This FOA must be used for all requests for support to continue existing CECs or establish new CECs.

Cohorts established to assess the role of exposures in the workplace on risk of cancer (i.e., “occupational cohorts”) may be appropriate for this FOA, but only if they were established to examine a broad range of exposures potentially experienced by the general public and/or genomic factors affecting cancer risk outcomes after cancer diagnosis. Cohorts focusing primarily on cancer risks associated with exposures in the workplace are not appropriate for this FOA.

This FOA is intended to support cohorts established to identify factors that increase or decrease the risk of developing cancer or the incidence of health outcomes after cancer. Therefore, cancer surveillance activities and development and maintenance of registries of persons with particular characteristics that do not address identification of factors increasing or decreasing risk are not appropriate for this FOA.

The activities supported by this FOA include the establishment, maintenance, or upgrade of CEC core functions, such as recruitment, retention, and biospecimen collection. Methodological research to validate or evaluate new or existing approaches to core infrastructure functions is also appropriate.

Research projects relying on CEC infrastructure are NOT appropriate for this FOA and such projects are expected to seek support through appropriate research project mechanisms, such as investigator-initiated R01 and P01 grants.

Application receipt dates for 2011 are February 8, June 6, and October 10. The PAR expires July 11, 2013. A set of Frequently Asked Questions is now available.

The contact for general questions is Deborah M. Winn, Ph.D., Deputy Director, Division of Cancer Control and Population Sciences; e-mail:

  • Access the NIH Guide for Grants and Contracts for details: PAR-10-283External Web Site Policy

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