EGRP News Flash - January 20, 2011

Request for Information: Interagency Breast Cancer and Environmental Research Coordinating Committee

On behalf of the Interagency Breast Cancer and Environmental Research Coordinating Committee (IBCERCC), the Epidemiology and Genetics Research Program (EGRP) announces the release of a Request for Information directed toward addressing questions relevant to the Committee’s mandate to develop a comprehensive summary of advances and recommendations regarding research gaps and needs for the HHS Secretary. The deadline for receipt of responses is February 16, 2011.

Input is sought on the below topics. Comment on each one is optional.

  1. How susceptibility to the effects of environmental exposures in sub-groups of the population (resulting from factors such as genetic or epigenetic variability, or timing of exposure during development or other stages) impacts breast cancer risk.
  2. Differences in the type and extent of environmental exposures which help explain the differential distribution of breast cancer subtypes in the U.S. population.
  3. How windows of susceptibility during the life-course can be integrated into a complex systems biology approach to better understand the role of the environment and breast cancer.
  4. How additional insight into normal mammary gland development through research using cell lines and animal models can enhance our understanding of environmental exposures and mammary carcinogenesis.
  5. The technologies and analytic capacity needed to accurately measure environmental exposures (including biological dose) and to develop markers of early damage relevant to breast cancer risk.
  6. The translation of research findings to the public about the environment and breast cancer risk considering the timing, and the strength of evidence, and the roles of community and advocacy groups.
  7. Engagement of advocacy organizations to ensure that environmental exposures of greatest interest and concern are studied and the role of media, data access, and publication access in this process.
  8. Approaches and effective models for coordination and collaboration among research agencies of the Federal Government to identify emerging opportunities in and programs to study environmental causes of breast cancer, such as in peer review, collaborative program development, and models for supporting cross-agency opportunities.

IBCERCC is a congressionally mandated body established by the National Institute of Environmental Health Sciences (NIEHS), in collaboration with the National Cancer Institute (NCI).

Send responses to IBCERCC ( by:

  • copying and pasting the questions into the body of an e-mail message and sending your responses to, or
  • mailing or faxing your responses in a letter to the attention of Jennifer B. Collins at the below address:

    Jennifer B. Collins, M.R.
    Program Analyst
    Division of Extramural Research and Training
    National Institute of Environmental Health Sciences
    National Institutes of Health
    U.S. Department of Health and Human Services
    P.O. Box 12233 (MD K3-12)
    Research Triangle Park, NC 27709-2233
    Telephone: 919-541-0117
    FAX: 919-541-2860

Access the NIH Guide for Grants and Contracts for details: NOT-ES-11-006External Web Site Policy.

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