EGRP News Flash - February 2, 2012
NIH Announces Two RFAs for Health Care Systems Research Collaboratory
The National Institutes of Health's (NIH) Common Fund is soliciting applications through two Requests for Applications (RFAs) for the Health Care Systems (HCS) Research Collaboratory program. The overall goal of the program is to strengthen the national capacity to implement cost-effective large-scale research studies that engage health care delivery organizations as research partners. The aim of the program is to provide a framework of implementation methods and best practices that will enable the participation of many health care systems in clinical research, not to support a defined health care research network. Research conducted in partnership with health care systems is essential to strengthen the relevance of research results to health practice. Learn more about the HCS Research Collaboratory.
The HCS Research Collaboratory RFAs are for:
Pragmatic Clinical Trials Demonstration Projects - Phase Innovation Awards Cooperative Agreement (Uh3/Uh4) - This RFA is soliciting applications for cooperative agreements for Demonstration Projects for efficient, large-scale pragmatic clinical trials. Pragmatic trials are defined as trials "primarily designed to determine the effects of an intervention under the usual conditions in which it will be applied," in contrast with explanatory trials which "are primarily designed to determine the effects of an intervention under ideal circumstances." (http://www.cmaj.ca/cgi/content/full/180/10/E47)
The Collaboratory will be well-suited to measuring both the negative and positive health impacts, as well as resource implications, of treatments delivered in real world settings. Demonstration Projects will be selected based both on the importance of the scientific questions and the potential to address impediments to research with health care delivery organizations.
Awards made through this RFA will initially support a one-year milestone-driven planning phase (Uh3), with possible rapid transition to the second implementation phase (Uh4) for a pragmatic trial Demonstration Project. The Common Fund intends to commit $5 million in Fiscal Year (FY) 2012 for approximately 10 Uh3 (Planning Phase) awards, and $15 million in FY 2013-2016 for up to five subsequent Uh4 (Implementation Phase) Demonstration Projects, contingent upon receiving scientifically meritorious applications.
Letters of Intent are due April 2, 2012 (although not required). The application deadline is May 2, 2012, by 5 p.m. local time of the applicant organization.
A videocast on Wednesday, February 29, 2012, from 2:30 to 4:30 p.m. EST will review the purpose and objectives of the Pragmatic Trials Demonstration Project RFA and address questions from the community.
NIH Guide for Grants and Contracts details:
Coordinating Center - Specialized Center Cooperative Agreement (U54) - The purpose of this RFA is to solicit applications for a Coordinating Center to provide national leadership for the NIH Health Care Systems (HCS) Research Collaboratory program. The Coordinating Center will 1) develop, adapt, and adopt technical and policy guidelines and best practices for the effective conduct of research studies in partnership with health care systems; 2) work collaboratively with each Demonstration Project team, including their partnering health care systems, to develop and test an implementation plan for the proposed Demonstration Projects while providing technical, design, and coordination support; and 3) disseminate widely Collaboratory endorsed policies and practices and lessons learned in the Demonstration Projects to inform best practices for broad participation of health care systems and their patients, practitioners, and staff in research studies to improve health and care delivery. The Coordinating Center will also serve as the central resource for the activities of the HCS Research Collaboratory program, including providing administrative support for the Steering Committee and its subcommittees.
One award is anticipated from this solicitation. The total amount of funds available is approximately $2 million for FY 2012 contingent upon receiving scientifically meritorious proposals.
Letters of Intent are due March 27, 2012 (although not required). The application deadline is April 27, 2012, by 5 p.m. local time of the applicant organization.
A videocast on Friday, February 17, 2012, from 2:00 to 4:00 p.m. EST will review the purpose and objectives of the Coordinating Center RFA and address questions from the community.
NIH Guide for Grants and Contracts details: