British Columbia Generations Project

Lead Contacts and/or Principal Investigators (PIs):

Funded Since: 2008
Funding Source: Canadian Partnership Against Cancer, BC Cancer Foundation
Year(s) of Enrollment: 2008-2016
Study Website: http://www.bcgenerationsproject.caExternal Web Site Policy

The BC Generations Project (BCGP) was initiated in 2008 by the BC Cancer Agency, in collaboration with similar prospective cohorts in Alberta (Tomorrow Project), Ontario (Ontario Health Study), Quebec (CARTaGENE), and the Atlantic provinces (Atlantic Path), in a national program to form a health research platform called the Canadian Partnership for Tomorrow Project.

The intent of the BC Generations Project (and the Canadian Partnership for Tomorrow) is to study the relationship between exposure to environmental, lifestyle, and genetic factors and the incidence of cancer and other chronic diseases. The program is supported nationally by the Canadian Partnership Against Cancer (CPAC) and regionally by a number of organizations. In British Columbia, financial support comes from the BC Cancer Foundation.

Over the time period 2009-2016, BCGP recruited almost 30,000 British Columbia residents aged 35 to 69 years from the general population. Participants were asked to complete a detailed questionnaire on lifestyle and medical history at cohort enrollment, and donate a 33 ml blood sample from which serum, plasma, red blood cells, and lymphocytes are isolated. Random urine samples were also requested. Blood and urine products are aliquoted and stored in both -80℃ and vapor phase LN freezers. Physical measurement data including blood pressure, lung function, bone density, and several other measures are collected on a sample of cohort members at entry. Between 2015 and 2016 participants were invited to complete a residential history questionnaire.

As well as linkage with the BC Cancer Registry, participants have given permission for BCGP to prospectively follow their health status through information held in electronic data banks of the British Columbia Ministry of Health. Cohort members have also given permission for further future direct contact.

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