COnsortium of METabolomics Studies (COMETS)
COnsortium of METabolomics Studies (COMETS)
- Mission and Objectives
- Proposing New COMETS Projects and Collaborations
- COMETS Inaugural Meeting
Mission and Objectives
The COnsortium of METabolomics Studies (COMETS) is an extramural-intramural partnership that promotes collaboration among prospective cohort studies that follow participants for a range of outcomes and perform metabolomic profiling of individuals. The objectives of COMETS are to:
- Provide a framework to foster international collaborations among studies sharing common objectives;
- Provide a forum for the discussion, development and pursuit of new collaborative studies and research directions;
- Support the development of early career researchers; and
- Advance the knowledge of the metabolome to improve our understanding of prediction of disease etiology, diagnosis and prognosis.
Based on these objectives, the aim of COMETS is to facilitate an open exchange of ideas, knowledge, and results in order to accelerate the study of metabolomics profiles associated with chronic disease phenotypes (e.g. heart disease, diabetes, cancer).
Membership Eligibility for Studies
Cohorts must meet the following criteria:
- Prospective cohort, 100+ participants with blood metabolomics data
- Identified metabolite data
- Follow-up for disease, including cancer and non-cancer outcomes
- Mass-spectrometry platform, preferred; however, NMR data are eligible
COMETS members are expected to comply with the consortium's bylaws.
Membership Categories for Investigators
Prospective members may apply to one of three membership categories within COMETS that can be applied for:
Steering Committee: Steering Committee members represent prospective cohort studies that have measured metabolomic profiles on their participants. At present, Steering Committee membership requires the represented study to have measured metabolomic profiles in blood using either mass-spectrometry or nuclear magnetic resonance (see membership eligibility above). However, as the technology advances and the COMETS consortium matures, this stipulation is open to modification. Steering Committee membership entitles individuals to vote, as well as to participate in Working Groups and become Working Group chairs. Membership is effective upon notification to and confirmation of acceptance by the current Steering Committee.
Consortium Member: Consortium members represent methodologic experts and/or investigators who are working in the field of metabolomics using metabolomic profiles measured in prospective cohort study participants. They are eligible to propose investigations to the Steering Committee for approval. Members are further required to maintain active participation in at least one working group and may become working group chairs. Membership is effective upon notification to and confirmation of acceptance by the Steering Committee. All Steering Committee members are Consortium Members, but not all Consortium Members are members of the Steering Committee. Consortium Membership alone does not provide voting rights for the Steering Committee.
Investigators interested in joining COMETS should fill out the form below and e-mail the completed form to Krista Zanetti, Ph.D., M.P.H., R.D.
Affiliate Member: Affiliate members can be either predoctoral or postdoctoral fellows or trainees who are part of a team led by either a Steering Committee or Consortium Member. They may lead or co-lead a project sponsored by a Steering Committee or Consortium Member and are eligible to transition to Member status upon transition to an independent research position. Affiliate members have no voting rights or eligibility for the Steering Committee.
Non-Affiliate Member: Non-affiliate membership is available to non-affiliated methodologic experts and requires nomination by a Steering Committee member. Members are further required to maintain active participation in at least one Working Group and may become Working Group chairs. Investigators who are interested in membership require a nomination by a Steering Committee member. Membership is effective upon acceptance by the Steering Committee.
Investigators interested in becoming a non-affiliate member should fill out the form below and discuss with your sponsor. After sponsor approval, please submit this application along with your CV to Ella Temprosa, Ph.D. or Krista Zanetti, Ph.D., M.P.H., R.D.
Proposing New COMETS Projects and Collaborations
The 2018 deadlines for submitting proposals are Tuesday, April 10, Friday, August 10 and Monday, December 10. Although investigators can submit proposals at any time throughout the year, they will not be reviewed until after the next deadline closest to the time of submission.
COMETS Inaugural Meeting
COMETS was established at a meeting that took place at the NCI on October 28-29, 2014, "Think Tank on Metabolomics and Prospective Cohorts: How to Leverage Resources."
For questions about COMETS or to inquire about becoming a member, contact Krista Zanetti, Ph.D., M.P.H., R.D.