Think Tank on Metabolomics and Prospective Cohorts: How to Leverage Resources


Purpose

The "Think Tank on Metabolomics and Prospective Cohorts: How to Leverage Resources," identified resources that can be used collaboratively across prospective cohorts; developed strategies to leverage resources for advancing the use of metabolomics in prospective cohort studies; identified the best strategies for performing analyses using metabolomics data across multiple studies; and, established a collaborative group, the COnsortium of METabolomics Studies (COMETS), that will identify and tackle research projects that cannot be effectively investigated by one independent group.

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Agenda


View Agenda for Tuesday, October 28, 2014
Time Topic
11:00 a.m. - 11:30 p.m. Registration
11:30 p.m. - 11:40 a.m. Welcome and Introductions
Deborah Winn, Ph.D.
National Cancer Institute
11:40 a.m. - 11:55 p.m. Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO)
Steven Moore, Ph.D., M.P.H. National Cancer Institute
11:55 p.m. - 12:10 p.m. Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (ATBC)
Demetrius Albanes, M.D. National Cancer Institute
12:10 p.m. - 12:25 p.m. Cancer Prevention Study – II (CPS-II)
Victoria Stevens, Ph.D.
American Cancer Society
12:25 p.m. - 12:40 p.m. Nurses' Health Study, Health Professional Follow-up Study, Physician's Health Study, Women's Health Initiative
Brian Wolpin, M.D., M.P.H.
Dana-Farber Cancer Institute
12:40 p.m. - 12:55 p.m.

ColoCare, Women's Health Initiative
Nina Habermann, Ph.D.
German Cancer Research Center

Neli Ulrich, Ph.D.
Huntsman Cancer Institute, University of Utah

12:55 p.m. - 1:10 p.m. Health Professional Follow-up Study (Prostate Cancer)
Kathryn Wilson, Sc.D.
Harvard School of Public Health
1:10 p.m. - 2:00 p.m. Lunch
2:00 p.m.-2:15 p.m. Shanghai Women's Health Study, Shanghai Men's Health Study
Xiao-ou Shu, M.D., Ph.D.
Vanderbilt University
2:15 p.m. - 2:30 p.m. Coronary Artery Disease Screening Trial and The Environmental Determinants of Diabetes in the Young
Tomas Cajka, Ph.D.
University of California, Davis Genome Center
2:30 p.m. - 2:45 p.m. Atherosclerosis Risk in Communities Study
Eric Boerwinkle, Ph.D.
University of Texas Health Science Center at Houston
2:45 p.m. - 3:00 p.m. Framingham Heart Study
Robert Gerszten, M.D.
Massachusetts General Hospital/Harvard Medical School
3:00 p.m. - 3:15 p.m. Catheterization Genetics and Genetics of Early Onset Cardiovascular Disease
Svati Shah, M.D., M.H.S.
Duke Molecular Physiology Institute
3:15 p.m. - 3:30 p.m. Women's Health Initiative (Cardiovascular Disease)
Kathryn Rexrode, M.D., M.P.H.
Brigham and Women's Hospital/Harvard Medical School
3:30 p.m. - 3:45 p.m. Multi-Ethnic Study of Atherosclerosis and COMBI-BIO
David Herrington, M.D.
Wake Forest School of Medicine
3:45 p.m. - 4:00 p.m. Health, Aging, and Body Composition Study
Tamara Harris, M.D., M.S.
National Institute of Aging
4:00 p.m. - 4:25 p.m. Break
4:25 p.m. - 4:40 p.m. TwinsUK
Cristina Menni, Ph.D.
King's College London
4:40 p.m. - 4:55 p.m.

Diabetes Prevention Program Outcomes Study
William Knowler, M.D., Ph.D., M.P.H.
National Institute of Diabetes and Digestive and Kidney Diseases

Yong Ma, Ph.D.
George Washington University

4:55 p.m. - 5:10 p.m. University College London, London School, Edinburgh and Bristol Consortium
Juan Pablo-Casas, M.D., Ph.D.
London School of Hygiene and Tropical Medicine/University of College London
5:10 p.m. - 5:30 p.m. Data Sharing: Definitions and Concepts
Deborah Winn, Ph.D.
National Cancer Institute
5:30 p.m. - 5:40 p.m. Summary
Joshua Sampson, Ph.D.
National Cancer Institute
5:40 p.m. - 6:30 p.m. Discussion
7:30 p.m. Group Dinner

View Agenda for Wednesday, October 29, 2014
Time Topic
8:00 a.m. - 8:05 a.m. Introduction
Joshua Sampson, Ph.D.
National Cancer Institute
8:05 a.m. - 8:25 a.m. LC-MS-Based Metabolic Profiling of Human Cohorts
Clary Clish, Ph.D.
Broad Institute of MIT and Harvard
8:25 a.m. - 8:45 a.m. Metabolomics and the Measurement of the Exposome in Epidemiological Studies
Augustin Scalbert, Ph.D.
International Agency for Research on Cancer
8:45 a.m. - 9:05 a.m. Quantitative Serum NMR Metabolomics Platform for Large-Scale Epidemiology and Genetics
Peter Würtz, Ph.D.
University of Oulu
9:05 a.m. - 9:15 a.m. Introduction/Objectives for the Day
Krista Zanetti, Ph.D., R.D., M.P.H.
National Cancer Institute
9:15 a.m. - 10:00 a.m. Breakout Groups
10:00 a.m. - 10:10 a.m. Break
10:10 a.m. - 10:40 a.m. Reports from Breakout Groups
10:40 a.m. - 11:00 a.m. Identify Key Collaboration Objectives
11:00 a.m. - 12:00 p.m. Discussion of Research Priorities: Identify Short- and Long-Term Goals
12:00 p.m. - 12:45 p.m. Lunch
12:45 p.m. - 1:00 p.m. Consortia Structures
Krista Zanetti, Ph.D., R.D., M.P.H.
National Cancer Institute
1:00 p.m. - 1:45 p.m. Discussion of Collaboration Structure
1:45 p.m. - 2:00 p.m. Next Steps and Wrap-up

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Meeting Summary

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