Metabolomics and Epidemiology Working Group


The Metabolomics and Epidemiology (MetEpi) Working Group was established in 2012 to promote strategies to develop capacity to support metabolomics analyses in population-based studies, as well as to advance the field of metabolomics for broader biomedical and public health research.

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Krista Zanetti, Ph.D., M.P.H., R.D.
Program Director, Genomic Epidemiology Branch

With the rapid advancement of technology in the past decade, metabolomics has enabled scientists to measure hundreds, or in some cases thousands, of unique chemical entities with mass spectrometry and nuclear magnetic resonance spectroscopy. Integration of metabolomics into epidemiologic or population-based study design has yet to be fully realized; yet exciting opportunities exist, especially as relates to non-communicable diseases.


The primary mission of the MetEpi Working Group is to leverage resources across government agencies in order to facilitate activities aimed at developing, facilitating, and supporting new and existing approaches for the use of metabolomics technologies in epidemiology research studies across various disease states.

The goals of the MetEpi Working Group are to:

  • Develop, facilitate, and support the use of metabolomics technologies in population-based research across various disease states through the missions of multiple federal partners at NIH, Food and Drug Administation (FDA) and the U.S. Department of Agriculture (USDA), including the National Cancer Institute (NCI); the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); the National Heart, Lung and Blood Institute (NHLBI), National Institute of Environmental Health Sciences (NIEHS), the Agricultural Research Service (ARS), and the National Center for Toxicological Research.
  • Collaborate and coordinate within or across agency stakeholders to issue joint funding opportunities for the use of metabolomics technologies in population-based research.
  • Conduct portfolio analyses to identify current research funding in the area of metabolomics in population-based research and to determine gaps and future needs.
  • Conduct and publish commentaries, opinion papers, and reviews on federal funding and the state of the field for metabolomics analyses being conducted in population-based research.

Steering Committee