November 2018 Cancer Epidemiology Matters E-News
Cancer Epidemiology Matters E-News
- How to Stay Up-to-Date with the National Cancer Institute’s Scientific Research Directions
- Genetic Simulation Software for Your Genetic Analysis Needs
How to Stay Up-to-Date with the National Cancer Institute’s Scientific Research Directions
Check out the National Cancer Advisory Board (NCAB) and Board of Scientific Advisor (BSA) meetings to find out about:
- NCI’s research directions
- Potential NCI funding opportunities being proposed
The next joint NCAB-BSA meeting is December 3-5, 2018. Watch the public webcast via NIH’s videocast.nih.gov site. The recorded videos for NCAB and BSA meetings are archived and available for later viewing.
The agenda for the December 3-5 meeting includes presentations about concepts for RFAs/Cooperative Agreements, such as:
- Research on pediatric, adolescent, and young adult cancer survivorship through the Childhood Cancer Survivorship Treatment, Access, and Research (STAR) Act
- Patient engagement for priority cancer sequencing (PE4PC)
- Optimizing management and outcomes for cancer survivors transitioning to follow-up care
Other resources to learn about progress and future directions of NCI research programs include:
Genetic Simulation Software for Your Genetic Analysis Needs
As genomic data have grown in size and complexity, there has been a need for the development of more sophisticated tools to analyze this data. Genetic simulation programs model data under specific assumptions and generate standardized datasets required for the comparison and evaluation of analytical tools. Therefore, genetic simulations play a critical role in developing new analytical methods.
To help researchers identify the genetic simulation program that best fits their research needs, NCI developed the Genetic Simulation Resources (GSR) catalogue. GSR contains detailed information on features of and generated data and typical applications for more than 140 simulators. Its search and comparison tools allow users to easily identify the most suitable simulators for their specific research topics.
Identifying High-Quality Research Tools
Simulators in GSR can also be designated as GSR-certified, meaning that they have been evaluated for the following four attributes: Accessibility, Documentation, Application, and Support. A GSR certification ensures that the simulator is reasonably easy to install and use, has decent documentation and support, and has been used by other researchers in the community. GSR simulators can be evaluated for each attribute (e.g., documentation) individually, but only simulators that meet all four criteria are classified as "GSR-certified." It is hoped that evaluating tools based on these criteria will encourage use of standards in the community and ensure that these programs are more readily findable and usable, as consistent with the FAIR principles. Detailed information on the GSR Certification Program is available on the GSR website and in a recent issue of Bioinformatics.
Certified simulators will be listed prominently on the GSR website and users will be able to easily search for GSR-certified software. Authors of GSR-certified resources can also place a special "GSR-certified" tile on their websites. For more information on getting a simulation package certified, please visit the GSR Certification Program page.
We Need Your Help!
The GSR Certification Committee needs volunteers to help review simulation packages and provide feedback on the future development of GSR. By volunteering, you can help facilitate the dissemination of these software programs and ensure the quality and usability of genetic simulation software for research needs. If you would like to volunteer, please email the GSR team. Researchers can also help by registering a simulator with GSR or spreading the word about this important resource.
GSR is supported by the Epidemiology and Genomics Research Program (EGRP) and the Surveillance Research Program (SRP) in NCI’s Division of Cancer Control and Population Sciences (DCCPS). Comments or questions about GSR should be directed to firstname.lastname@example.org