PHARMO Record Linkage System


The PHARMO Record Linkage System links six major sources of data and includes information on 2 million residents in the Netherlands. The linked data sources provide information on outpatient drug exposure; hospital admissions; discharge diagnoses; diagnostic, surgical, and treatment procedures; consultations with medical practitioners; in-hospital drug use; clinical laboratory procedures ordered by general practitioners and specialists; clinical and prescription drug data from general practitioners, and histological, cytological, and autopsy examinations. The System was established at the Utrecht and Rotterdam Universities in the early 1990s. The database provides insight into the effectiveness, safety, and economic value of prescription drugs as used in daily practice.

Selected References


Beiderbeck-Noll AB, Sturkenboom MC, van der Linden PD, Herings RM, Hofman A, Coebergh JW, Leufkens HG, Stricker BH. Verapamil is associated with an increased risk of cancer in the elderly: the Rotterdam studyExternal Web Site Policy. Eur J Cancer. 2003 Jan;39(1):98-105.

Beiderbeck AB, Holly EA, Sturkenboom MC, Coebergh JW, Stricker BH, Leufkens HG. Prescription medications associated with a decreased risk of non-Hodgkin's lymphomaExternal Web Site Policy. Am J Epidemiol. 2003 Mar 15;157(6):510-6.

Graaf MR, Beiderbeck AB, Egberts AC, Richel DJ, Guchelaar HJ. The risk of cancer in users of statinsExternal Web Site Policy. J Clin Oncol. 2004 Jun 15;22(12):2388-94.

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