Krista A. Zanetti, Ph.D., M.P.H., R.D.

Program Director
Genomic Epidemiology Branch, Epidemiology and Genomics Research Program

Telephone: (240) 276-6843
Fax: (240) 276-7920

  • Ph.D. - Nutrition, Cornell University
  • M.P.H. - Epidemiologic and Biostatistical Methods for Public Health and Clinical Research, The Johns Hopkins Bloomberg School of Public Health
  • B.S. - Clinical Dietetics and Nutrition, University of Pittsburgh
Contact for questions about:
  • Metabolomics
  • Integration of “omics” with genomics


Dr. Krista Zanetti is a Program Director in the Genomic Epidemiology Branch (GEB) of the Epidemiology and Genomics Research Program (EGRP) in NCI's Division of Cancer Control and Population Sciences (DCCPS). Her responsibilities include managing a portfolio of grants that includes metabolomics, integration of 'omics data with genomics data, and rare cancers. She is involved in trans-agency and trans-NIH activities that address the use of metabolomics technologies in population-based research to accelerate cancer biomarker discovery. In this capacity, Dr. Zanetti is the NCI co-coordinator of the NIH Metabolomics Common Fund Program, a member of the Human Health Exposure Analysis Resource (HHEAR) Executive Committee, the Program Officer for the COnsortium of METabolomics Studies (COMETS) and the Chair of the NIH Metabolomics Scientific Interest Group.

Prior to joining EGRP, Dr. Zanetti was a Research Fellow in NCI's Laboratory of Human Carcinogenesis (LHC), Center for Cancer Research. Her studies explored biological determinants that contribute to cancer health disparities and the association of common allele variants with cancer risk. Dr. Zanetti first came to NCI as a Cancer Prevention Fellow in LHC.

Select Publications

Stevens VL, Hoover E, Wang Y, Zanetti KA. Pre-Analytical Factors that Affect Metabolite Stability in Human Urine, Plasma, and Serum: A Review. Metabolites. 2019 Jul 25;9(8). pii: E156.

Yu B, Zanetti KA,Temprosa M, Albanes D, Appel N, Barrera CB, Ben-Shlomo Y, Boerwinkle E, Casas JP, Clish C, Dale C, Dehghan A, Derkach A, Eliassen AH, Elliott P, Fahy E, Gieger C, Gunter MJ, Harada S, Harris T, Herr DR, Herrington D, Hirschhorn JN, Hoover E, Hsing AW, Johansson M, Kelly RS, Khoo CM, Kivimäki M, Kristal BS, Langenberg C, Lasky-Su J, Lawlor DA, Lotta LA, Mangino M, Le Marchand L, Mathé E, Matthews CE, Menni C, Mucci LA, Murphy R, Oresic M, Orwoll E, Ose J, Pereira AC, Playdon MC, Poston L, Price J, Qi Q, Rexrode K, Risch A, Sampson J, Seow WJ, Sesso HD, Shah SH, Shu XO, Smith GCS, Sovio U, Stevens VL, Stolzenberg-Solomon R, Takebayashi T, Tillin T, Travis R, Tzoulaki I, Ulrich CM, Vasan RS, Verma M, Wang Y, Wareham NJ, Wong A, Younes N, Zhao H, Zheng W, Moore SC. The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies. Am J Epidemiol. 2019 Jun 1;188(6):991-1012.

van Roekel EH, Loftfield E, Kelly RS, Zeleznik OA, Zanetti KA. Metabolomics in epidemiologic research: challenges and opportunities for early-career epidemiologists. Metabolomics. 2019 Jan 7;15(1):9.

Beger RD, Dunn WB, Bandukwala A, Bethan B, Broadhurst D, Clish CB, Dasari S, Derr L, Evans A, Fischer S, Flynn T, Hartung T, Herrington D, Higashi R, Hsu PC, Jones C, Kachman M, Karuso H, Kruppa G, Lippa K, Maruvada P, Mosley J, Ntai I, O'Donovan C, Playdon M, Raftery D, Shaughnessy D, Souza A, Spaeder T, Spalholz B, Tayyari F, Ubhi B, Verma M, Walk T, Wilson I, Witkin K, Bearden DW, Zanetti KA. Towards quality assurance and quality control in untargeted metabolomics studies. Metabolomics. 2019 Jan 3;15(1):4.

Zanetti KA, Mette E, Maruvada P, Milner J, Moore SC, Nicastro HL, Ross SA, Sampson JN, Verma M, Su LJ. The future of metabolomic profiling in population-based research: opportunities and challengesExternal Web Site Policy. J Anal Bioanal Tech. 2014 5(4), doi: 10.4172/2155-9872.1000203

Haznadar M, Maruvada P, Mette E, Milner J, Moore, SC, Nicastro HL, Sampson JN, Su LJ, Verma M, Zanetti KA. Navigating the road ahead: addressing challenges for use of metabolomics in epidemiology studiesExternal Web Site Policy. Metabolomics. 2014 April;10(2):176-8.