Biospecimen Resources for Population Scientists
Leveraging Existing Biospecimen Resources to Advance Cancer Epidemiology Research - 3/29/12
- Potential Sources of Biospecimens for Investigators
- Policies and Best Practices for Biospecimen Research
Potential Sources of Biospecimens for Investigators
This list provides links to biospecimen resources that may be of interest to cancer epidemiologists, but is not exhaustive. Access to resources is dependent on procedures outlined for each individual study or resource. Availability may depend on suitability of proposed research, collaboration with study investigators, ethical considerations, approval from a steering committee, or availability of samples to perform study.
Compiled Lists and Search Tools for Sources of Biospecimens
- Australasian Biospecimen Network Tissue Specimen Locator
Locate tissue specimens within the Australia and New Zealand biobanking communities.
- NCI Specimen Resource Locator
Search specimen banks and procurement services to find human tissue, serum, DNA/RNA, and other specimens.
- NCI Research Resources
Find resources on human specimens, animal specimens, tissue microarrays of human tumors, specimen banks and procurement services, and validation of biomarkers.
- NCI Division of Cancer Treatment and Diagnosis - Human Tissue Specimen Resources
Find human tissue specimen resources from the Cancer Diagnosis Program.
- National Heart, Lung, and Blood Institute's (NHLBI) Biological Specimen and Data Repository Information Coordinating Center (BioLINCC)
Learn about NHLBI open collections, request data and/or biospecimens, and register study information.
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Central Repository
Locate phenotypic data and biological samples.
- NIH Office of Rare Diseases Research Biospecimens/Biorepositories Website: Rare Disease-HUB (RD-HUB)
Search database containing collected, stored, and distributed biospecimens by biorepositories in the United States and worldwide.
- National Cancer Research Institute (NCRI) Resource Catalogue
Access a catalog of biospecimen collections in the UK.
Biospecimen Information for NCI-Supported Studies
Agricultural Health Study (AHS)*
AIDS and Cancer Specimen Resource (ACSR)
Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (ATBC)*
Atherosclerosis Risk in Communities Study (ARIC)*
Black Women's Health Study*
Breast and Colon Cancer Family Registries (CFRs)
Carotene and Retinol Efficacy Trial (CARET)
Cooperative Breast Cancer Tissue Resource (CBCTR)
Cooperative Human Tissue Network (CHTN)
Health Professionals Follow-Up Study (HPFS)*
The North American Breast Cancer Group (NABCG)
The Nurses' Health Study (NHS)*
Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial*
Southern Community Cohort Study (SCCS)*
Southwest Oncology Group (SWOG) - Prostate Cancer Prevention Trial (PCPT)
Surveillance Epidemiology and End Results (SEER) Residual Tissue Repository (RTR) Program
Women's Health Initiative (WHI)
*This cohort is a member of NCI's Cohort Consortium.
Other Study-Specific Biospecimen Information
In this section are other studies, biobanks, and resources with biospecimens with procedures for access or sharing of biospecimens.
- Australasian Biospecimen Network (ABN)-Oncology (ABN)
- Chernobyl Tissue Bank
- Danish National Biobank
Search the biobank register and apply to access samples and data from the Danish National Biobank.
- Electronic Medical Records and Genomics (eMERGE) Network
- Environmental Polymorphism Registry
- Framingham Heart Study
- NIH Common Fund Project: Genotype-Tissue Expression (GTEx) Project
Find and apply to access tissue, DNA, RNA, and cell lines from the GTEx study.
- Janus Serum Bank
- Kaiser Permanente Research Program on Genes, Environment and Health (RPGEH)
Identify and apply to access RPGEH data and biospecimens.
- National Health and Nutrition Examination Survey (NHANES) Stored Biologic Specimens
- UK Biobank
Apply to access biospecimens from 500,000 people between the ages of 40-60 years from the UK.
- The Wales Cancer Bank
Policies and Best Practices for Biospecimen Research
NIH Biospecimen Resources
- NIH Biospecimens Interest Group
This group disseminates information, best practices, and ethical/legal information regarding biospecimens.
- Biorepositories and Biospecimen Research Branch, Division of Cancer Treatment and Diagnosis, NCI
Website constains information about several biospecimen resources and references that may be useful in the design of research studies.
- NIH Common Fund, Genotype-Tissue Expression (GTEx) Project Standard Operating Procedures (SOPs)
SOPs for Ethnical and Regulatory, Biospecimen Collection, Data Collection, and Pathology Review Procedures for GTEx.
- NCI Think Tank on Identifiability of Biospecimens and -Omic Data Workshop Summary [PDF - 1.98 MB]
The purpose of this Think Tank, convened in June 2012, was to bring together a multidisciplinary group of experts to explore challenges surrounding the identifiability of genomic data and biospecimens. The resulting considerations regarding consent policy development, data access and security policies, proposed best practices, and opportunities for empirical research, are summarized in this report.
Other Biospecimen Resources
- International Society for Biological and Environmental Repositories (ISBER)
ISBER provides several resources for biobanking and biospecimens, including the ISBER best practices and a tool for evaluating adherence to these practices.
- Public Population Project in Genomics (P3G)
This consortium encourages collaboration between researchers and biobankers by promoting harmonization of information, optimizing design, set-up and research activities of biobanks, and facilitating the transfer of knowledge within the field.
Epidemiology and Genomics Research Program (EGRP) contacts for questions about biospecimens related to cancer epidemiology research:
- Danielle Carrick, Ph.D., M.H.S., EGRP Biospecimens Coordinator and Program Director, Host Susceptibility Factors Branch (HSFB)
- Leah Mechanic, Ph.D., M.P.H., Program Director, HSFB
- Sheri Schully, Ph.D., Program Director and Lead, Knowledge Intregration Team, Office of the Associate Director