Infectious Agents and Cancer Epidemiology Research Webinar Series


Purpose

The Epidemiology and Genomics Research Program (EGRP) hosts a quarterly webinar series, "Infectious Agents and Cancer Epidemiology Research." The goals of this series are to:

  • Highlight emerging and cutting-edge research related to infection-associated cancers that could be applied to cancer epidemiology;
  • Share scientific knowledge about technologies and methods that may enhance and facilitate infection-associated cancer epidemiology research; and
  • Foster cross-disciplinary discussions on infectious agents and cancer epidemiology.

Any interested individual is invited to participate. The webinars are free, but require pre-registration. Each presentation will be about 30 minutes in length and allow for 30 minutes of discussion moderated by EGRP staff. Instructions for connecting to the webinars will be sent via e-mail to individuals who register.

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Background

Infections are established etiologic factors in several cancers and contribute significantly to the global cancer burden. In 2008, it was estimated that 16.1% of newly diagnosed cancers were attributable to infections. The translational potential for this area of research is significant, as the identification of infections associated with cancers may lead to interventions such as treatment or vaccines to prevent associated cancers. As discussed in a blog post by NCI, DCCPS, EGRP, epidemiologic studies on the interplay of infectious agents and cancer induction could play important roles in answering both old and new questions, which could augment current knowledge and open new areas of research. Understanding the role of infectious agents in cancer may result in discoveries that could lead to better diagnosis, prevention, and treatment of cancers, particularly in resource-poor areas.

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Upcoming Topics and Speakers

July 11, 2018 2:00 p.m. to 3:00 p.m. ET

Gastric Cancer Trends in the U.S.

Maria Constanza Camargo, Ph.D.
Earl Stadtman Investigator, Division of Cancer Epidemiology and Genetics, National Cancer Institute


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Note: Additional speakers and topics may be added in the future.

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Past Topics and Speakers

May 10, 2018 2:00 p.m. to 3:00 p.m. ET

Molecular Epidemiology of Epstein-Barr Virus Co-Infection in Gastric Carcinogenesis

Charles Rabkin, M.D.
Senior Investigator
Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute


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Dr. Charles Rabkin earned an Sc.B. and M.D. from Brown University and an M.Sc. in epidemiology from the London School of Hygiene and Tropical Medicine. He received postgraduate training at the University of Colorado and is board certified in internal medicine and preventive medicine. Before coming to the NCI, he was an Epidemic Intelligence Service Officer and a medical epidemiologist at the Centers for Disease Control and Prevention. He has received PHS Commendation and Unit Commendation Medals for his studies of non-Hodgkin lymphoma and Kaposi sarcoma and the Outstanding Service Medal for the molecular epidemiology of Helicobacter pylori and HIV-related malignancies.

Dr. Rabkin’s research is directed toward understanding the molecular mechanisms underlying associations of chronic infection and inflammation, particularly for gastric cancer and non-Hodgkin lymphoma.

His work in gastric cancer encompasses three sub-projects on the pathogenic microbes, modifying host factors and intermediate markers with potential for screening of gastric cancer and pre-neoplastic lesions. He has a particular focus on the Epstein-Barr virus (EBV) as a co-factor with Helicobacter pylori, the established cause of most cancers of the noncardia stomach. His work in Non-Hodgkin lymphoma focuses on the acquired and inherited abnormalities of immune cells that may contribute to their malignant transformation.

Dr. Rabkin presented on the molecular epidemiology of Epstein-Barr virus co-infection in gastric carcinogenesis.


December 11, 2017 2:00 p.m. to 3:00 p.m. EST

Shifting Trends in Cancer Risk and Burden Among People Living with HIV in the United States

Meredith Shiels, Ph.D., M.H.S.
Investigator
Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute


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Dr. Shiels' research focuses on trends in cancer incidence and mortality, and the contribution of risk factors to these trends. She has a particular expertise in understanding cancer risk and burden among HIV-infected people, and is the co-Principal Investigator (PI) of the NCI’s HIV/AIDS Cancer Match Study. In this webinar, Dr. Shiels presented on the shifting trends in cancer risk and burden among people living with HIV in the United States.


September 21, 2017 1:00 p.m. to 2:00 p.m. EDT

HPV Natural History in HIV+ Women and Its Clinical Implications

Howard D. Strickler, M.D., M.P.H.External Web Site Policy
Head of the Division of Epidemiology and Harold & Muriel Block Chair in Epidemiology
Department of Epidemiology and Population Health, Albert Einstein College of Medicine


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Dr. Howard Strickler presented on the HPV natural history in HIV+ women and relevant clinical complications. He is internationally recognized for his work on human papillomavirus (HPV) natural history in women who test positive for human immunodeficiency virus (HIV). His research has had a major impact on the current clinical guidelines for cervical cancer screening in women with HIV.


June 29, 2017 1:00 p.m. to 2:00 p.m. EDT

Epidemiology and Perinatal Transmission of Kaposi's Sarcoma-Associated Herpesvirus in Sub-Saharan Africa

Charles Wood, Ph.D.External Web Site Policy
Director
Nebraska Center for Virology, University of Nebraska-Lincoln, School of Biological Sciences


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Dr. Wood's work focuses on HIV/AIDS and associated malignancies. He has served as the PI of several multi-center and multi-national collaborative projects, including serving as a Project Director for Biomedical Research Excellence award with 15-year funding from the NIH National Center for Research Resources (NCRR) to establish and sustain the Nebraska Center for Virology and serving as PI of a Fogarty International training grant on AIDS and associated malignancies. His largest ongoing collaborative research projects involve multiple U.S. research institutions, the University of Zambia School of Medicine and the University Teaching Hospital to study HIV/AIDS and Kaposi's sarcoma-associated herpesvirus (KSHV) transmission, disease pathogenesis, treatment and prevention. In this webinar Dr. Wood presented on the epidemiology and perinatal transmission of KSHV in Sub-Saharan Africa.


April 11, 2017 10:00 a.m. to 11:00 a.m. ET

The EMBLEM Study: A Resource for Molecular and Immunological Studies of Endemic Burkitt Lymphoma in East Africa

Sam Mbulaiteye, MBChB, M.Phil., M.Med.
Senior Investigator
Division of Cancer Epidemiology & Genetics (DCEG), National Cancer Institute


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Dr. Mbulaiteye presented on the Epidemiology of Burkitt's Lymphoma in East-African Children and Minors (EMBLEM) Study, a multi-country and multi-year case-control study that is evaluating the role of repeated malarial infections, malaria genetic variants, and Epstein-Barr virus genetic variants in Burkitt's lymphoma.


December 1, 2016 2:00 p.m. to 3:00 p.m. EST

HPV Infection in Men, HPV Vaccine Trials, and the Role of HPV in Cancers

Anna R. Giuliano, Ph.D.External Web Site Policy
Founding Director, Center for Infection Research in Cancer (CIRC)
Moffitt Cancer Center


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Dr. Anna Giuliano is the Founding Director of the Center for Infection Research in Cancer (CIRC) at the Moffitt Cancer Center. Her primary research focus is on the relationship between human papillomavirus (HPV) infections and cancer, including cervical, penile, anal, and oral cancers. Her work has contributed to the understanding of the rate at which HPV infections are acquired and cleared, the proportion that progress to disease, and HPV vaccine protection against multiple diseases in women and men. Dr. Giuliano presented on HPV infection in men, HPV vaccine trials, and the role of HPV in cancers.


September 20, 2016 11:30 a.m. to 12:30 p.m. EDT

Cutaneous Viral Infections as Potential Risk Factors for the Development of Non-Melanoma Skin Cancers

Dana E. Rollison, Ph.D.External Web Site Policy
Vice President, Chief Health Information Officer
Associate Member, Department of Cancer Epidemiology, Moffitt Cancer Center


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Dr. Dana Rollison is currently the PI of the NCI-funded VIRUSCAN Study, a 5-year, prospective cohort study of cutaneous viral infections, UV exposure and risk of basal and squamous cell carcinomas being conducted among skin cancer screening patients attending the University of South Florida Dermatology Clinic. She is also collaborating with investigators in the Immunology Program to identify markers of immune function that may predispose to both cutaneous viral infections and NMSC. Her primary research focus is the molecular epidemiology of human polyomavirus and papillomavirus infections in relation to cancer. In this webinar, Dr. Rollison discussed cutaneous viral infections as potential risk factors for the development of non-melanoma skin cancers.


June 9, 2016 2:00 p.m. to 3:00 p.m. EDT

Annual Report to the Nation with a Focus on Liver Cancer: Risk Factors and Burden Are Unevenly Distributed in the Population

Sean Altekruse, D.V.M., M.P.H., Ph.D.
Epidemiologist, Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute
Captain, Commissioned Corps of the U.S. Public Health Service


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Dr. Sean Altekruse is an epidemiologist in the Surveillance Informatics Branch (SIB) of the Surveillance Research Program (SRP). His research interests include infection and cancer and prognostic tumor biomarkers. He is also the National Cancer Institute PI for the National Longitudinal Mortality Study. Dr. Altekruse presented on population-based liver cancer surveillance.


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EGRP Planning Committee

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Contact

Questions about individual webinars or the series may be submitted via e-mail to the EGRP Planning Committee at IAandCancer@mail.nih.gov.

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