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Epidemiology and Genomics Research Program

Pharmacogenomics Resources

The resources on this page provides links to resources that may be of interest to cancer researchers interested in the area of pharmacogenomics, but is not exhaustive.

Collaborative Opportunities, Consortia and Networks

  • Clinical and Translational Science Awards (CTSAs)
    Under the leadership of the NIH National Center for Advancing Translational Sciences (NCATS), the Clinical and Translational Science Awards (CTSA) Program supports a national network of medical research institutions — called hubs― that work together to improve the translational research process to get more treatments to more patients more quickly. The hubs collaborate locally and regionally to catalyze innovation in training, research tools and processes.
  • Critical Path Institute (C-Path)External Web Site Policy
    The Critical Path Institute (C-Path) is a nonprofit, public-private partnership with  the Food and Drug Administration (FDA). C-Path’s aim is to accelerate the pace and reduce the costs of medical product development through the creation of new data standards, measurement standards, and methods standards that aid in the scientific evaluation of the efficacy and safety of new therapies.
  • Electronic Medical Records and Genomics (eMerge) NetworkExternal Web Site Policy
    eMERGE is a national network organized and funded by the National Human Genome Research Institute (NHGRI) that combines DNA biorepositories with electronic medical record (EMR) systems for large-scale, high-throughput genetic research in support of implementing genomic medicine.
  • Human Genome Epidemiology Network (HuGENet)
    Initiated by the Centers for Disease Control and Prevention (CDC), the Human Genome Epidemiology Network, or HuGENet™, helps translate human genetic research findings into opportunities for preventive medicine and public health.
  • Pharmacogenetics Research Network (PGRN)
    The NIH Pharmacogenetics Research Network (PGRN), led by the National Institute of General Medical Sciences (NIGMS), is a network of scientists focused on understanding how a person’s genes affect his or her response to medicines.
  • Serious Adverse Events Consortium (SAEC)External Web Site Policy
    The international Serious Adverse Events Consortium (SAEC) is a non-profit biomedical research organizations. It is comprised of leading pharmaceutical companies, the Wellcome Trust, and academic institutions, with scientific and strategic input from the U.S. Food and Drug Administration (FDA) and other international regulatory bodies. Its mission is to identify DNA variants useful in understanding the risk of drug-related serious adverse events (SAEs).


  • Database of Genotypes and Phenotypes (dbGaP)
    The database of Genotypes and Phenotypes (dbGaP) is a database initiated by the NIH's National Library of Medicine (NLM) and is part of the National Center for Biotechnology Information (NCBI). dbGap was developed to archive and distribute the results of studies that have investigated the interaction of genotype and phenotype in humans.
  • Database of Single Base Nucleotide Substitutions (dbSNP)
    The Database of Single Base Nucleotide Substitutions (dbSNP) is the National Center for Biotechnology Information (NCBI) central repository for human single nucleotide variations, microsatellites, and small-scale insertions and deletions along with publication, population frequency, molecular consequence, and genomic and RefSeq mapping information for both common variations and clinical mutations.
  • Pharmacogenomics Knowledge Base (PharmGKB)External Web Site Policy
    PharmGKB is a publicly available Internet research tool developed by Stanford University with funding from the NIH. The PharmGKB is a pharmacogenomics knowledge resource that encompasses clinical information, potentially actionable gene-drug associations, and genotype-phenotype relationships.

Knowledge Synthesis Resources

  • Genotype-Tissue Expression (GTEx) Project
    This NIH Common Fund program established a data resource and tissue bank to study the relationship between genetic variation and gene expression in multiple human tissues.


  • PhenXExternal Web Site Policy
    PhenX is a project led by RTI International, and funded by the National Human Genome Research Institute (NHGRI), with co-funding by the National Institute on Drug Abuse (NIDA), is helping to integrate genetics and epidemiologic research. The PhenX Toolkit includes more than 700 measurement protocols addressing 25 research domains and providing additional depth in specific research domains.