Resources - Genetic Associations and Mechanisms in Oncology (GAME-ON) Initiative

Tools Created by GAME-ON Investigators

GAME-ON investigators developed tools that can be used by the scientific community to further their research. More tools may be added to this page over time.

  • FunciSNP: an R/bioconductor tool integrating functional non-coding data sets with genetic association studies to identify candidate regulatory SNPs.External Web Site Policy

    The R/Bioconductor software package enables the identification of candidate functional SNPs by integrating information from tagSNP locations, lists of linked SNPs from the 1000 genomes project and locations of chromatin features which may have functional significance.

    FunciSNP is available from Bioconductor.External Web Site Policy

  • GAME-ON GWAS Look-Up ToolExternal Web Site Policy

    The GAME-ON GWAS look-up tool allows users to find association results between single nucleotide polymorphisms (SNPs) and overall as well as estrogen receptor negative (ER-) breast cancer risk. Users are able to search for a specific SNP, by gene or by genetic region.

  • GeneSigDB - a curated database of gene expression signatures.External Web Site Policy

    GeneSigDBExternal Web Site Policy is a searchable resource providing access to gene signatures that have been manually curated from the literature and mapped to standard gene identifiers using a defined annotation pipeline. These standardized gene signatures facilitate the use of gene set enrichment methods and the search for common features among published datasets.

  • GxEscanExternal Web Site Policy: software to detect GxE interactions in a genome-wide association study. GxEscan implements a variety of exhaustive and 2-step testing approaches. GxEscanExternal Web Site Policy is available for download from the University of Southern California.