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Epidemiology and Genomics Research Program

July 2024 EGRP Cancer Epidemiology News

EGRP Cancer Epidemiology News


Enabling Large-Scale Data Collaborations: NCI Cohort Consortium and CEDCD

NCI’s Epidemiology and Genomics Research Program (EGRP) in the Division of Cancer Control and Population Sciences (DCCPS) supports a number of resources for facilitating research across the cancer control continuum.

The NCI Cohort Consortium is an extramural-intramural partnership that promotes large-scale collaborations to pool data and biospecimens necessary to conduct a wide range of studies using prospective longitudinal data. Through its collaborative network of investigators, the consortium provides a coordinated, interdisciplinary approach to tackling important scientific questions, economies of scale, and opportunities to quicken the pace of research.

To date, NCI Cohort Consortium members have launched more than 80 scientific initiatives, and more than 200 publications have resulted from Cohort Consortium projects. The consortium’s Project Hub is a searchable database in which users can view active and completed consortium projects and affiliated publications as well as submit new project proposals and update their progress. The Hub can provide useful information for users deciding whether to join a current project, submit a new proposal to address an identified research gap, or communicate directly with the project leaders to discuss opportunities to collaborate on new or existing research ideas within the consortium. Cohort Consortium members and other interested researchers may propose and conduct a study with the consortium – one does not need to be associated with a member cohort to submit a project application.

Since the consortium’s inception, foundational work in genome-wide association studies in breast and prostate cancers has fostered more expansive work in developing polygenic risk scores. The consortium has unique resources to address research of rarer cancers, which require collaboration among multiple studies to gather sufficient data. Examples include the studies of the association between vitamin D and rarer cancers, such as ovarian and pancreatic cancers and studies focused on risk factors for appendiceal, gallbladder, and biliary tract cancers. Learn more about participating in the NCI Cohort Consortium.

Anyone interested in the Cohort Consortium’s annual meeting is welcome to attend either in-person or virtually. The annual meeting will be held at the NCI Shady Grove campus in Rockville, MD on November 12-15, 2024. Please visit the Cohort Consortium annual meeting website for more details about the meeting and registration, which is now open.

In addition to coordinating the NCI Cohort Consortium’s activities, EGRP supports cohort-related resources for researchers, such as the Cancer Epidemiology Descriptive Cohort Database (CEDCD). The CEDCD is a searchable database containing general study information for the cohorts (e.g., eligibility criteria and size); the type of data collected at baseline, including type of biospecimens and number of participants diagnosed with cancer; and key contacts for each cohort. The goal of the CEDCD is to facilitate collaboration and highlight the opportunities for research within existing cohort studies.

The collaborative research activities facilitated by the NCI Cohort Consortium and resources such as the CEDCD advance the goal of DCCPS to improve the health of the public through cancer control.

New Funding Opportunities

  • RFA-OD-24-010, Building Sustainable Software Tools for Open Science (R03, Clinical Trial Not Allowed)
  • RFA-OD-24-011, NIH Research Software Engineer Award (R50, Clinical Trials Not Allowed)
  • PHS 2024-2 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications
    • PA-24-245 (Parent SBIR[R43/R44], Clinical Trial Not Allowed)
    • PA-24-246 (Parent SBIR [R43/R44] Clinical Trial Required)
  • PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications
    • PA-24-247 (Parent STTR [R41/R42], Clinical Trial Not Allowed)
    • PA-24-248 (Parent STTR [R41/R42], Clinical Trial Required)
  • NOT-CA-24-073, Notice of Special Interest (NOSI): Factors Impacting How Time-Restricted Eating (TRE) Influences Cancer-Related Outcomes
  • NOT-CA-24-064, NOSI: Dissemination and Implementation Science for Cancer Prevention and Control in Low Resource Environments
  • NOT-OD-24-146, NOSI: Improving Adherence to Treatment and Prevention Regimens and Maintenance of Health Behaviors to Promote Health
  • Notice of Intent to Publish a Funding Opportunity Announcement for the Confluence of Cancer Stigma and HIV Stigma in HIV-positive Individuals Diagnosed with Cancer
  • NOT-CA-24-075, Notice of Intent to Publish a Funding Opportunity for Scaling-up and Maintaining Evidence-based Interventions to Maximize Impact on Cancer (SUMMIT) - Lung Cancer Screening (UG3/UH3, Clinical Trial Required)
  • NOT-CA-24-076, Notice of Intent to Publish a Funding Opportunity for Scaling-up and Maintaining Evidence-based Interventions to Maximize Impact on Cancer (SUMMIT) - Tobacco Use Treatment for Cancer Survivors (UG3/UH3, Clinical Trial Required)
  • NOT-CA-24-070, Notice of Intent to Publish a Funding Opportunity Announcement for NCI Research Specialist (Clinical Scientist) Award (R50, Clinical Trial Not Allowed)

New Requests for Proposals

  • NOT-OD-24-134, Extramural Loan Repayment Program for Clinical Researchers
  • NOT-OD-24-135, Extramural Loan Repayment Program for Pediatric Research
  • NOT-OD-24-136, Extramural Loan Repayment Program for Health Disparities Research
  • NOT-OD-24-137, Extramural Load Repayment Program for Research in Emerging Areas Critical to Human Health
  • NOT-OD-24-138, Extramural Clinical Research Loan Repayment Program for Individuals from Disadvantaged Backgrounds

Grants Policy Announcements

  • NOT-OD-24-123, Reporting Data Management and Sharing Plan Activities in the Research Performance Progress Report
  • NOT-OD-24-149, Prior Approval Requirement for Changes to Domestic Subawards for the SBIR and STTR Programs
  • NOT-OD-24-157, Implementation Update for Data Management and Access Practices Under the Genomic Data Sharing Policy
  • NOT-OD-24-151, Single Audit Requirements for Foreign Recipients and Subrecipients of NIH Grants

Requests for Information

Research Resources

  • NOT-PM-24-004, Enabling Research, Training, and Career Development by Analyzing Data Collected by the All of Us Research Program

Career Opportunities

Training Opportunities

  • NOT-OD-24-103, NIH Entrepreneurship Boot Camp for pre-SBIR/STTR Innovators (submissions due by August 16, 2024)

News and Blog Posts

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