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Epidemiology and Genomics Research Program

June 2024 EGRP Cancer Epidemiology News

EGRP Cancer Epidemiology News

Dr. Erin Siegel Named Associate Director of NCI’s Epidemiology and Genomics Research Program

Dr. Erin Siegel has been named Associate Director of the Epidemiology and Genomics Research Program (EGRP) for the National Cancer Institute's (NCI) Division of Cancer Control and Population Sciences (DCCPS). EGRP is the largest funder of cancer epidemiologic research worldwide; its focus is to support research in human populations to understand determinants of cancer occurrence and outcomes.

Prior to joining NCI in June 2024, Dr. Siegel was a Senior Member in the Departments of Cancer Epidemiology and Gastrointestinal Oncology at the Moffitt Cancer Center and Research Institute. She was also an Associate Professor in the Department of Oncologic Sciences in the University of South Florida’s College of Medicine. Dr. Siegel had an administrative leadership position as the inaugural Scientific Director of Moffitt’s Non-Therapeutic Research Office, a unique office dedicated to supporting the conduct of observational and cancer epidemiology studies.

Dr. Siegel has a wealth of experience building and leveraging patient cohorts and biorepositories to advance high-impact team science. She was a (Multiple) Principal Investigator of the ColoCare study — a large, multi-institutional, cohort study investigating outcomes among colorectal cancer (CRC) patients — and established the Moffitt ColoCare Site in 2009. She was a co-Investigator on several NIH research project grants (R01) that leveraged the infrastructure of the cohort to identify prognostic and predictive proteomic and metabolomic biomarkers of CRC recurrence, identify metabolomic and genomic predictors of cancer-related fatigue, and examine the association of body composition on CRC outcomes.

In addition, Dr. Siegel was instrumental in leading and providing strategic direction of Moffitt’s institutional biobanking protocol — the Total Cancer Care Protocol (TCC) — for over 10 years and served as PI since 2021. She was an active collaborator, leveraging TCC resources for research spanning multiple cancers, including CRC, multiple myeloma, and lung, kidney, and head and neck cancers. She has used multi-omics approaches to identify pan-cancer circulating biomarkers, including emerging biomarkers within exosomes, and has conducted molecular and clinical epidemiological studies focused on HPV-associated cervical, anal, and head and neck cancers.

Dr. Siegel’s recent scientific interests include cancer epidemiology and cancer survivorship research spanning lifestyle/behavioral factors, racial/ethnic disparities, and translational studies aimed at discovering and validating novel molecular, blood-based biomarkers related to the risk of adverse CRC outcomes.

Dr. Siegel has also been involved with and provided leadership to the Oncology Research Information Exchange Network (ORIEN) since 2014, most recently as its Steering Committee Chair. ORIEN is a national research network of 18 cancer centers in the United States that are focused on accelerating cancer research and advancing care through collaboration and partnerships.

Dr. Siegel earned both her PhD and MPH degrees in epidemiology from the Arizona College of Public Health, University of Arizona, in Tucson.

Funding Opportunities

  • PAR-24-207, Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01, Clinical Trials Optional)
  • RFA-CA-24-027, Addressing Barriers to Healthcare Transitions for Survivors of Childhood and Adolescent Cancers (R01, Clinical Trial Optional)
  • RFA-DA-25-026 , HEAL Initiative: JCOIN Phase II Community Engaged Research Resource Center (U24, Clinical Trial Optional)
  • RFA-NR-24-006, Understanding the Intersection of Social Inequities to Optimize Health and Reduce Health Disparities: The Axes Initiative (R01, Clinical Trial Optional)
  • NOT-CA-24-056, Notice of Special Interest (NOSI): Mechanisms Driving Obesity and Prostate Cancer Risk
  • NOT-CA-24-060, NOSI: Advancing Diet and Physical Activity Biomarkers for Assessing Lifestyle Interventions in Cancer Prevention and Cancer Interception Research
  • NOT-OD-24-119, NOSI: Research Opportunities Centering the Health of Women Across the HIV Research Continuum
  • NOT-MD-24-018, Notice of Intent to Publish a Funding Opportunity Announcement for Environmental Health Disparities Centers (P50)

Grants Policy Announcements

  • NOT-CA-24-063, Preapplication Webinar: Addressing Barriers to Healthcare Transitions for Survivors of Childhood and Adolescent Cancers
  • NOT-OD-24-129External Web Site Policy, Updates to NIH Institutional Training Grant Applications for Due Dates on or After January 25, 2025
  • NOT-OD-24-123External Web Site Policy, Reporting Data Management and Sharing (DMS) Plan Activities in the Research Performance Progress Report (RPPR)

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