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Epidemiology and Genomics Research Program

August 2025 EGRP Cancer Epidemiology News

EGRP Cancer Epidemiology News

August 2025

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Promoting Research Data Re-Use

Through its data sharing policies, NIH has had a long-standing commitment to making data from its funded projects available for replication and for secondary research use. Consistent with this commitment, scientific data from many NCI-funded studies overseen by NCI’s Epidemiology and Genomics Research Program (EGRP) have been shared in NIH repositories. The datasets listed below are all available in the database of Genotypes and Phenotypes (dbGaP).

  • In addition to participating in genetic and genomic studies that are required by NIH to share their data, NCI-funded cohorts have shared complementary and tangential data in dbGaP, often with extensive non-genomic data collected by the cohort.
  • The Center for Inherited Disease Research (CIDR) program is funded by NIH to conduct high-quality data generation for approved grantees. Among its services, CIDR works with NCI-funded investigators (including many with grants managed in EGRP) to make their CIDR-generated data available to the broader scientific community.
  • The Index of NCI studies lists additional dbGaP datasets from grants funded by NCI and managed by the Division of Cancer Control and Population Sciences (DCCPS).

All these datasets can be requested through the dbGaP Authorized Access system. Approximately 130 of the studies in dbGaP are from EGRP’s grants portfolio.

NCI leads two funding opportunities that promote the use of the datasets referenced above:

  • Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes

Applicants to these funding opportunities are encouraged to leverage existing data and perform innovative analyses of the existing data. Applications may include new aims that are being addressed with existing data, new or advanced methods of analyses, or novel combinations and integration of datasets that allow the exploration of important scientific questions. These PARs expire on September 8, 2026. The EGRP contact for these PARs is Melissa Rotunno, PhD.

More information on data freely available to researchers for cancer-related population science studies can be found in the Cancer Epidemiology Descriptive Cohort Database, EGRP’s list of biospecimen resources, and a public datasets and analyses web page hosted by DCCPS.

Funding Opportunities

  • RFA-RM-25-003, NIH Director’s Transformative Research Awards (R01, Clinical Trial Optional)
  • RFA-RM-25-002, NIH Director's New Innovator Award Program (DP2, Clinical Trial Optional)
  • RFA-RM-25-001, NIH Director's Pioneer Award Program (DP2, Clinical Trial Optional)
  • PAR-25-437, Environmental Influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Access (X01, Clinical Trial Not Allowed)
  • PAR-25-414, Support for Research Excellence (SuRE) Award (R16, Clinical Trial Not Allowed)
  • PAR-25-415, Support for Research Excellence – First Independent Research (SuRE-First) Award (R16, Clinical Trial Not Allowed)
  • PAR-25-337, Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01, Clinical Trial Optional)
  • Ruth L. Kirschstein National Research Service Award (NRSA)
    • PA-25-422 (Individual Predoctoral Fellowship, Parent F31)
    • PA-25-423 (Individual Postdoctoral Fellowship, Parent F32)
    • PA-25-424 (Individual Senior Fellowship, Parent F33)
    • PA-25-425 (Individual Fellowship for Students at Institutions Without NIH-Funded Predoctoral Dual-Degree Training Programs, Parent F30)
    • PA-25-426 (Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs, Parent F30)
  • Extramural Loan Repayment Program
  • Informatics Technologies for Cancer Research (ITCR) Grant Opportunity Forecasts
    • FOR-CA-25-075, Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
    • FOR-CA-25-074, Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)
    • FOR-CA-25-073, Early-Stage Development of Informatics Technologies for Cancer Research and Management (U01 Clinical Trial Optional)

Grants Policy Announcements

  • NOT-OD-25-121, Temporary Extension of Eligibility for the NIH Pathway to Independence Award (K99/R00)
  • NOT-OD-25-124, Notice of Rescission of Civil Rights Term and Condition of Award
  • NOT-OD-25-128, Guidance on Enforcement of Closeout Requirements During the Appeals Process
  • NOT-OD-25-130, Updated Implementation Guidance of NIH Policy on Foreign Subawards for Active Projects
  • NOT-OD-25-131, Revision: NIH Policy and Guidelines on the Inclusion of Women and Minorities as Subjects in Clinical Research
  • NOT-OD-25-132, Supporting Fairness and Originality in NIH Research Applications
  • NOT-OD-25-133, NIH Announces a New Policy Requirement to Train Senior/Key personnel on Other Support Disclosure Requirements
  • NOT-OD-25-134, Flexibilities for Registration and Results Reporting of Prospective Basic Experimental Studies with Human Participants

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Last Updated: 15 Aug, 2025