Danielle Daee, Ph.D.
Program Director, Genomic Epidemiology Branch

Address:
Epidemiology and Genomics Research Program
Division of Cancer Control and Population Sciences
National Cancer Institute
National Institutes of Health
9609 Medical Center Drive, Rm. 4E236, MSC 9763
Bethesda, MD 20892
(For express delivery, use Rockville, MD 20850)

Interest Areas

  • Genetic susceptibility to cancer

Degrees

  • Ph.D. - Pathology and Microbiology with training in Cancer Research
    University of Nebraska Medical Center
  • B.S. - Biology, Minor Chemistry
    Truman State University

Biography

Dr. Danielle Daee is a Program Director in the Genomic Epidemiology Branch (GEB) of the Epidemiology and Genomics Research Program (EGRP) in NCI's Division of Cancer Control and Population Sciences (DCCPS). Her responsibilities include managing a portfolio of grants related to genetic factors modulating susceptibility to cancer in general and in pediatric cancers specifically. Notably, Dr. Daee represents EGRP on the Gabriella Miller Kids First Pediatric Research Program working group. Dr. Daee also supports the assessment and evaluation of several ongoing EGRP initiatives.

Prior to joining EGRP, Dr. Daee was a Health Science Analyst in NCI's Office of Science Planning and Assessment (OSPA). In this position, she evaluated the impact of NCI’s research investments by performing and consulting on program assessments and portfolio analyses.

Dr. Daee was a postdoctoral fellow at the National Human Genome Research Institute (NHGRI) at NIH before joining NCI. During her fellowship, she identified and studied yeast homologs in the Fanconi Anemia DNA repair pathway. Through her research career, Dr. Daee developed an expertise in DNA repair, DNA replication, and yeast genetics.

Publications

Kochenova OV, Daee DL, Mertz TM, Shcherbakova PV. DNA Polymerase zeta-dependent lesion bypass in Saccharomyces cerevisiae is accompanied by error-prone copying of long stretches of adjacent DNA. PLoS Genetics. 2015 Mar;11(3):e1005110.

Daee DL, Myung K. Fanconi-like crosslink repair in yeast. Genome Integrity. 2012 Oct;3(1):7.

Daee DL, Ferrari E, Longerich S, Zeng XF, Xue X, Branzei D, Sung P, Myung K. RAD5-dependent DNA repair functions of the Saccharomyces cerevisiae FANCM homolog Mph1. J Biol Chem. 2012 Aug;287(32):26563-75.

Daee DL, Myung K. Small RFC subunits make a big difference. Cell Cycle. 2010 Nov;9(22):4429.

Yan Z, Delannoy M, Ling C, Daee D, et al. A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Mol Cell. 2010 Mar;37(6):865-878.

Daee DL, Mertz TM, Shcherbakova PS. A cancer-associated DNA polymerase δ variant modeled in yeast causes a catastrophic increase in genomic instability. Proc Natl Acad Sci. 2010 Jan;107(1):157-162.

Erlich RL, Fry RC, Begley TJ, Daee DL, Lahue RS, Samson LD. Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae. PLoS ONE. 2008;3(11):e3717.

Daee DL, Mertz T, Lahue RS. Postreplication repair inhibits CAG·CTG expansions in Saccharomyces cerevisiae. Mol Cell Biol. 2007 Jan;27(1):102-110.

Lahue RS, Slater DL. DNA repair and trinucleotide repeat instability. Front Biosci. Review Article. 2003 May;8:s653-65.

Return to Top