Notices of Special Interest (NOSI)

What is a NOSI?

A NOSI is a standard, formal format for NIH Institutes to share and update their research priorities. Each NOSI describes aims in a specific scientific area and points to one or more funding opportunity announcements (FOAs) that investigators can apply to for support. The use of NOSIs represents a major change in how NIH Institutes and Centers communicate their research priorities to the research community and thus fill scientific gaps.

How Does a NOSI Work?

NOSIs describe specific topics of interest or areas of research and direct applicants to one or more active funding opportunity announcements (often a parent announcement), so that investigators may submit applications for the initiative described.

A NOSI is not an FOA and is listed as a notice in the NIH Guide for Grants and Contracts. Applicants should read NOSIs carefully for any special requirements related to that specific announcement. See NOT-OD-19-107 for additional information about NOSIs and where to direct general questions about them.

Most NOSIs require applicants to include the notice number in the Agency Routing Identifier field (4b) of the SF424 (R&R) form so NIH can assign and track applications and awards for the described initiative. It is critical that applicants adhere to this notice instruction. The notice number must be included in the Agency Routing Identifier field (field 4b on the SF424 R&R form) at the time of application submission.

Investigators considering a grant application that falls within the scientific areas of interest of the Epidemiology and Genomics Research Program (EGRP) are welcome to contact EGRP’s scientific program directors to discuss how research ideas fit within the strategic priorities of EGRP, the Division of Cancer Control and Population Sciences, and the National Cancer Institute.