Methods and Technologies

The Methods and Technologies Branch in NCI’s Epidemiology and Genomics Research Program supports innovative cancer epidemiology research, including development and adaptation of laboratory and technical approaches for large studies in human populations.

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Interest Areas

Program Directors

Investigators seeking grant funding for methods and technologies projects are encouraged to contact scientific staff in the Methods and Technologies Branch (MTB) with questions.

MTB Program Directors

Featured Funding Opportunities

Exploratory Grants in Cancer Control
PA-25-253 (R21, Clinical Trial Optional)
Expires September 8, 2028

Modular R01s in Cancer Control and Population Sciences
PA-25-172 (R01, Clinical Trial Optional)
Expires January 8, 2028

Assay Validation of High Quality Markers for Clinical Studies in Cancer
PAR-25-074 (UH2/UH3 – Clinical Trial Not Allowed)
PAR-25-075 (UH3 – Clinical Trials Not Allowed)
Expires October 15, 2026

Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants
PAR-24-304 (R01, Clinical Trial Not Allowed)
Expires October 15, 2026

NCI Small Grants Program for Cancer Research (NCI Omnibus)
PAR-25-078 (R03, Clinical Trial Optional)
Expires January 8, 2026

Bioengineering Research Grants
PAR-22-242 (R01 - Clinical Trial Not Allowed)
PAR-22-243 (R01 - Clinical Trial Optional)
Expires September 8, 2025

Notice of Special Interest: Utilization of Cohorts and Prospective Study Designs for Liquid Biopsy Assay Evaluation for Early Detection of Cancer
NOT-CA-23-004
Expires July 2, 2025

Notice of Special Interest: Technology Development for Cancer Control and Population Science Research
NOT-CA-23-037
Expires December 31, 2024

Notice of Special Interest: Technologies and Informatics Tools for Cancer Metabolomics
NOT-CA-22-083
Expires December 31, 2024

View all notices of funding opportunities related to cancer control research.

Interest Areas

Learn more about MTB’s interests in the following areas, relevant funding opportunity announcements, related EGRP events, and staff contacts.

Biomarkers

EGRP is interested in supporting research that improves understanding of how biomarkers can be used in early detection/screening of cancer.

Epigenomics and Epigenetics

EGRP is interested in supporting research to increase understanding of processes that regulate how and when certain genes are turned on and off may be deregulated in cancer.

Staff in EGRP partner with others at NCI and NIH to foster research to better understand the causes of health disparities and develop interventions to reduce differences in the incidence, prevalence, mortality, and burden of cancer and related adverse health conditions that exist among specific population groups in the United States.

Infectious Agents

EGRP partners with others at NCI and NIH to foster investigator-initiated research to better understand the role of infectious agents in cancer.

Metabolomics in Population-Based Research

EGRP staff and others at NCI and NIH are working together to advance the use of metabolomics technologies in epidemiology research.

Microbiome Research

Staff in EGRP partner with others at NCI and NIH to foster analysis of the microbiome and associated metabolites that may assist in the understanding of microbial exposures and their association with disease risk, incidence, progression, and treatment response.

Last Updated: 14 Nov, 2024